Evidence map›Paper›PMID 42325728›Full record

ArticleJournal of nutritional science2026

Dietary fish oil improves intestinal barrier function and intestinal microbiota composition and reduces systemic inflammation in a mouse model of moderate acute malnutrition.

Grace E Patterson, Elvia Yaneth Osorio, Sara M Dann, Peter C Melby

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nutritional science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Grace E PattersonMicrobiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, USA.
Elvia Yaneth OsorioInternal Medicine, The University of Texas Medical Branch at Galveston, USA.
Sara M DannInternal Medicine, The University of Texas Medical Branch at Galveston, USA.
Peter C MelbyMicrobiology and Immunology, The University of Texas Medical Branch at Galveston, Galveston, USA.ORCID https://orcid.org/0000-0001-7320-7406

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute malnutrition (wasting) remains a global public health problem. Ready-to-use therapeutic foods (RUTF) and supplemental foods (RUSF) for treatment of severe acute malnutrition (SAM) and moderate acute malnutrition (MAM), respectively, come in the form of macro- and micronutrient-dense pastes. These lipid-dense treatments provide the energy and nutrients needed to support growth but have significant rates of relapse. Their role in reversing pathophysiological contributors to malnutrition, such as intestinal barrier dysfunction, intestinal dysbiosis, and systemic inflammation have not been evaluated. Traditional lipid-dense RUTFs and RUSFs are rich in pro-inflammatory omega-6 polyunsaturated fatty acids (PUFAs) but low in anti-inflammatory omega-3 PUFAs, which could fuel malnutrition-related pathological inflammation. We reasoned that reduced dietary omega-6 (

Indexed as

Fish OilsGastrointestinal MicrobiomeInflammationIntestinal Barrier FunctionMalnutritionAnimalsCitrobacter rodentiumDisease Models, AnimalFatty Acids, Omega-3Fatty Acids, Omega-6IntestinesMaleMiceMice, Inbred C57BLFatty Acids, Omega-3Fatty Acids, Omega-6Fish OilsChildhood malnutritionFish oilInflammationIntestinal barrierMicrobiota

Identifiers

PMID42325728
PMCPMC13279968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.