Evidence map›Paper›PMID 42325725›Full record

ArticleF&S reports2026

Embryologist experience affects concordance with an artificial intelligence embryo ranking algorithm: benefit of artificial intelligence assistance.

Jørgen Berntsen, Philip Marsh, Brendan Burkart, Mark G Larman, Martin N Johansen, Mitchell Rosen

Abstract read
In one paragraph

Article in F&S reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jørgen BerntsenResearch and Development Medical Devices, Vitrolife Group, Viby, Denmark.
Philip MarshDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, California.
Brendan BurkartDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, California.
Mark G LarmanNorth American Medical Affairs, Vitrolife Group, Englewood, Colorado.
Martin N JohansenResearch and Development Medical Devices, Vitrolife Group, Viby, Denmark.
Mitchell RosenDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To study the concordance between artificial intelligence (AI) algorithm selection and manual embryo selection, and how the concordance depends on the experience levels of embryologists. Design: Retrospective observational study. Subjects: A total of 1,321 preimplantation genetic testing for aneuploidy (PGT-A) tested cycles from 1,165 patients with at least one transferred euploid embryo. Exposure: Embryo ranking was performed both manually and using an AI algorithm. Main Outcome Measures: The concordance rate between embryologists and an AI algorithm. Results: The overall concordance rate was 58.6% (95% confidence interval [CI]: 55.9%-61.2%) and increased with embryologist experience: Junior (51.3%, 95% CI: 44.3%-58.2%), Senior (57.1%, 95% CI: 53.3%-61.0%), and Senior+ (63.4%, 95% CI: 59.2%-67.7%). The fetal heartbeat (FHB) rates were 68.3% (95% CI: 65.1%-71.6%) in the concordant group and 66.5% (95% CI: 62.6%-70.5%) in the discordant group. The odds ratio between the two groups was not statistically significant, however when adjusting for the number of usable embryos, age and oocyte source, the odds ratio was significant. Conclusion: The concordance levels between embryologists and an AI algorithm depended significantly on the level of experience. The study also indicated that adjunctive use could potentially increase clinical outcomes.

Indexed as

concordancedeep-learningEmbryo selectiontime-lapse

Identifiers

PMID42325725
PMCPMC13282521

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.