Evidence map›Paper›PMID 42325679›Full record

ArticleFrontiers in cardiovascular medicine2026

A study on the correlation between novel inflammatory indices and severity of coronary artery lesions in patients with stable coronary artery disease.

Ying Li, Zinan Zhao, Hongxi Zhang, Botao Sang, Sainan Li, Dachuan Guo, Xiaohan Zhao, Xiangfei Liu, Xiaoshuo Li, Deping Liu

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Article in Frontiers in cardiovascular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Ying LiPeking University Fifth School of Clinical Medicine, Beijing, China.
Zinan ZhaoDepartment of Pharmacy, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Hongxi ZhangHealth Service Department of the Guard Bureau of the Joint Staff Department, Beijing, China.
Botao SangDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Sainan LiDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Dachuan GuoDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Xiaohan ZhaoDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Xiangfei LiuDepartment of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Xiaoshuo LiPeking University Fifth School of Clinical Medicine, Beijing, China.
Deping LiuPeking University Fifth School of Clinical Medicine, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: The novel inflammatory indices integrate information from multiple immune cells, but their application in stable coronary artery disease (SCAD) remains limited. This research aims to explore the association between the novel inflammatory indices and the degree of coronary artery lesions in SCAD patients. Methods: This retrospective analysis involved 2,424 patients of SCAD who received coronary angiography at Beijing Hospital from January 2021 to January 2024. Participants were assigned to groups with mild and severe coronary artery lesions according to the Gensini score. Based on whole blood cell parameters, we calculated the neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), platelet-lymphocyte ratio (PLR), systemic immune inflammation index (SII), systemic inflammatory response index (SIRI), and systemic immune inflammatory response index (SIIRI) and analyzed their links to the degree of coronary artery lesions. Results: All novel inflammatory indices exhibited positive associations with the Gensini score ( Conclusion: NLR, MLR, and SIRI demonstrate notable associations with the extent of coronary artery lesions in individuals with SCAD and can be used as non-invasive risk assessment indicators. This research provides novel perspectives for the study of inflammatory mechanisms and risk assessment of SCAD patients.

Indexed as

coronary arterycorrelationGensini scorenovel inflammatory indicesstable coronary artery disease

Identifiers

PMID42325679
PMCPMC13275256

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