ArticleOpen forum infectious diseases2026
Maternal and Newborn Group B
Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
12 authors.
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Abstract
Background: This descriptive seroepidemiology study characterized group B Methods: Healthy US and South African ≥18-year-olds at ≥34 weeks of pregnancy were enrolled. Exploratory analyses evaluated GBS serotype-specific (Ia, Ib, II, III, IV, and V) anticapsular polysaccharide (CPS) immunoglobulin G (IgG) geometric mean concentrations (GMCs) before and at delivery and in cord blood; newborn-to-maternal transplacental transfer ratios were determined. Results: We enrolled 722 maternal (United States, n = 273; South Africa, n = 449) and 592 newborn participants (n = 251; n = 341). Maternal GBS anti-CPS IgG GMCs were similar before and at delivery. A trend for higher GMCs (serotypes Ia, Ib, II, and III) among South African compared with US maternal participants was seen. As in maternal participants, GMCs for serotypes Ia and III trended higher among South African compared with US newborns. Mean transplacental transfer ratios were higher for US newborn-maternal pairs compared with South African dyads. Transplacental transfer ratios for serotypes Ia and Ib were >1 for US pairs. Among US participants, there was a trend for higher transplacental transfer ratios among White versus Black participants. Maternal hypergammaglobulinemia (gamma globulin >1.35 g/dL) was observed in 23.8% of South African participants and in no US participants. Conclusions: Group B
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