Evidence map›Paper›PMID 42325512›Full record

ArticleFrontiers in nutrition2026

Low 1,25-dihydroxyvitamin D levels are associated with severe COVID-19: an observational study in hospitalized patients.

Esra Canbolat Unlu, Semsi Nur Karabela, Zuhal Yesilbag, Ramazan Korkusuz, Deniz Borcak, Esra Salim Dogdas, Sevtap Senoglu, Nilgun Isiksacan, Kadriye Kart Yasar

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Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Esra Canbolat Unlu *Department of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.
Semsi Nur Karabela *Department of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.
Zuhal YesilbagDepartment of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.
Ramazan KorkusuzDepartment of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.
Deniz BorcakDepartment of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.
Esra Salim DogdasDepartment of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.
Sevtap SenogluDepartment of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.
Nilgun IsiksacanDepartment of Clinical Biochemistry, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.
Kadriye Kart YasarDepartment of Infectious Diseases and Clinical Microbiology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, University of Health Sciences, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aimed to evaluate the association of serum 25-hydroxyvitamin D (25(OH)D) and 1,25-dihydroxyvitamin D (1,25(OH) Methods: A total of 185 adult patients (≥18 years) with confirmed SARS-CoV-2 PCR positivity and without chronic kidney disease, admitted between March and May 2020, were included. Clinical characteristics, laboratory parameters, and serum 25(OH)D and 1,25(OH) Results: Of the patients, 114 had moderate disease and 71 had severe disease. Length of hospital stay, intensive care unit (ICU) admission, and mortality rates were significantly higher in the severe group. While 25(OH)D levels were lower in the moderate group, 1,25(OH) Conclusion: Reduced 1,25(OH)

Indexed as

1,25-dihydroxyvitamin D25-hydroxyvitamin DCOVID-19 severityhospitalized patientsprognostic biomarkervitamin D deficiency

Identifiers

PMID42325512
PMCPMC13279753

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.