Evidence map›Paper›PMID 42325381›Full record

ArticleCase reports in dermatological medicine2026

Severe Eczema Herpeticum With Ocular Involvement Leading to Orbital Cellulitis: A Pediatric Case Report.

Chu Han Chew, Mohamad Shahidatul-Adha, Ismail Abdul-Salim, Ee Ling Ang

Abstract read
In one paragraph

Article in Case reports in dermatological medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chu Han ChewDepartment of Ophthalmology, Hospital Pulau Pinang, Jalan Residensi, Georgetown, Penang, Malaysia, moh.gov.my.
Mohamad Shahidatul-AdhaDepartment of Ophthalmology and Visual Science, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian, Kota Bharu, Kelantan, Malaysia, usm.my.ORCID https://orcid.org/0000-0002-4835-4022
Ismail Abdul-SalimDepartment of Ophthalmology, Hospital Pulau Pinang, Jalan Residensi, Georgetown, Penang, Malaysia, moh.gov.my.
Ee Ling AngDepartment of Ophthalmology, Hospital Pulau Pinang, Jalan Residensi, Georgetown, Penang, Malaysia, moh.gov.my.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eczema herpeticum (EH) is a superimposed cutaneous viral infection that occurs in the context of preexisting dermatoses, most commonly atopic dermatitis (AD). It typically involves the face, neck, and upper trunk. Although ocular involvement is relatively uncommon, it may present diagnostic and therapeutic challenges and pose a significant risk to vision. We report a pediatric case of EH with severe ocular involvement in a young child with underlying AD. Despite early oral antiviral and antibiotic therapy, the condition progressed rapidly to orbital cellulitis. Clinical improvement was observed following escalation to intravenous antiviral therapy, addition of topical antiviral treatment, and broadening of antibiotic coverage, with subsequent full recovery. This case highlights the importance of early recognition, close monitoring, and timely escalation of treatment in EH with ocular involvement to prevent sight-threatening complications.

Indexed as

acycloviratopic dermatitiseczema herpeticumherpes zoster ophthalmicuspunched-out erosion

Identifiers

PMID42325381
PMCPMC13277754

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.