ArticleMagnetic resonance in medicine2026
T1-weighting in Steady-State FLASH MRI-Diffusion Is Not Only Supportive but Mandatory for the Contrast.
Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeFLASH imaging is widely assumed to produce a T
methodsFLASH sequences were simulated using phase graph simulations using a synthetic brain phantom with and without diffusion and realistic PD values to show the contrast change. The impact of neglecting diffusion in synthetic training data was evaluated using a segmentation network trained on simulated data and tested on in vivo measurement. Experimental validation of the contrast change was performed using a 3D-printed brain phantom using silicone oil as a low-diffusivity compartment.
resultsWithout diffusion, simulations showed CSF signal intensities higher than WM, resulting in a contrast change. Diffusion suppresses higher-order echoes in long T
conclusionDiffusion is essential for realistic FLASH simulations of long T
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