Evidence map›Paper›PMID 42324525›Full record

ArticleBMC pediatrics2026

The role of STORCH infections in shaping neurodevelopment: a longitudinal case-control study in preterm children.

Luana Marques, Alessandra Bombarda Muller, Carolina Panceri, Renato S Procianoy, Rita C Silveira, Nadia Cristina Valentini

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In one paragraph

Article in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luana MarquesSchool of Physical Education, Physical Theraphy and Dance, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
Alessandra Bombarda MullerDepartment of Physiotherapy, School of Health, Universidade do Vale do Rio dos Sinos (UNISINOS), Porto Alegre, Brazil.
Carolina PanceriSchool of Physical Education, Physical Theraphy and Dance, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil.
Renato S ProcianoyHospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil.
Rita C SilveiraHospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil.
Nadia Cristina ValentiniSchool of Physical Education, Physical Theraphy and Dance, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil. nadiacv@esef.ufrgs.br.ORCID 0000-0001-6412-5206

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Scholarship
6 · The paper itself

Abstract

Congenital infections, often asymptomatic for both mother and fetus, can affect neurodevelopment. This study aimed to analyze neurodevelopmental outcomes and associated risk factors in preterm children with and without congenital STORCH infections. A case-control study was conducted, with children assessed longitudinally. A retrospective case-control study was conducted including 248 preterm children. The control group showed higher cognitive and language scores than the STORCH case-group. The STORCH case-group had a significant decline in cognitive scores from 6 to 18 months (p<0.05), although their motor scores improved from 6 to 24 months (p<0.05). Risk factors for neurodevelopment in the STORCH case-group included APGAR, NICU seizures and stay, familyincome, sepsis, and twin birth (beta 0.27-0.49). For the control-group, risk factors included NICU seizures and stay, APGAR, family income, sepsis, mechanical ventilation, maternal education, and bronchopulmonary dysplasia (beta 0.12-0.31). Children with STORCH infections showed poorer cognitive and language development. Early prevention of STORCH infections is crucial to prevent negative developmental outcomes.

Indexed as

Child DevelopmentInfant, Premature, DiseasesNeurodevelopmental DisordersCase-Control StudiesChild, PreschoolFemaleHumansInfantInfant, NewbornInfant, PrematureLongitudinal StudiesMaleNeurodevelopmentRetrospective StudiesRisk FactorsChild developmentCongenital infectionNeurodevelopmentPreterm childrenRisk factors

Identifiers

PMID42324525
PMCPMC13539877

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.