Evidence map›Paper›PMID 42324477›Full record

ReviewJournal of eating disorders2026

A scoping review on weight loss injections and eating disorders: therapeutic impact, risks of misuse, and emerging harms.

Poppy Barrett, Cat Papastavrou Brooks, Sara McCluskey, Amy Brown

Abstract readReview
In one paragraph

Review in Journal of eating disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Poppy BarrettSPIRED Research Clinic, Sussex Partnership NHS Foundation Trust, Brighton, UK.
Cat Papastavrou BrooksSPIRED Research Clinic, Sussex Partnership NHS Foundation Trust, Brighton, UK. c.h.f.papastavrou-brooks@exeter.ac.uk.
Sara McCluskeySussex Eating Disorder Service, Sussex Partnership NHS Foundation Trust, Brighton, UK.
Amy BrownSPIRED Research Clinic, Sussex Partnership NHS Foundation Trust, Brighton, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimGLP-1 receptor and GIP agonists are widely used for weight loss in obesity, with strong evidence supporting their efficacy, and their potential positive impact on binge eating disorders. However, little is known about their use in individuals with eating disorders. Despite growing concerns, research exploring this intersection is limited, and clinical guidance is lacking.

objectivesThis scoping review explores existing literature on weight loss injections in the context of eating disorder development and treatment to identify gaps and inform future practice.

methodsThe scoping review searched six electronic databases (Embase, MEDLINE, PsycINFO, AMED, HMIC, and Emcare) in April 2025. Studies were eligible if they focused on the use of weight loss injections (GLP-1 receptor agonists), in individuals with current or past eating disorders, including all diagnoses. Both clinical and non-clinical settings were included, with no age or geographical restrictions.

resultsA total of 80 records were identified through database searches. After title and abstract screening, 11 full-text articles were assessed for eligibility. Two papers were excluded due to the absence of empirical data, resulting in 9 studies being included in the final review.

conclusionsOverall, there is very limited evidence exploring the psychological impact of GLP-1 receptor agonists on individuals with eating disorders. While some findings suggest potential benefits for managing binge eating symptoms in populations with comorbid type 2 diabetes, there is a significant gap in our understanding of how these medications may influence disordered eating behaviours and body image concerns, particularly when used outside of weight-based indicators. Further research is essential to inform clinical guidelines.

Indexed as

Binge eating disorderEating disordersGIP agonistsGLP-1 receptor agonistsWeight loss injections

Identifiers

PMID42324477
PMCPMC13491749

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.