Evidence map›Paper›PMID 42324421›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Biomechanical simulation of long-term performance of a tendon-based spinal stabilization (VPX).

Jana Felicitas Schader, Oliver Wigger, Marie-Rosa Fasser, Anna-Katharina Calek, Ramon Rohner, Anna Schuler, Niels Hammer, Jess G Snedeker, Mazda Farshad, Jonas Widmer

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

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Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Jana Felicitas Schader *Department of Orthopedics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland. jana.schader@balgrist.ch.
Oliver Wigger *Spine Biomechanics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Marie-Rosa FasserSpine Biomechanics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Anna-Katharina CalekDepartment of Orthopedics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Ramon RohnerSpine Biomechanics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Anna SchulerDepartment of Orthopedics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Niels HammerDivision of Macroscopic and Clinical Anatomy, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
Jess G SnedekerDepartment of Orthopedics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Mazda FarshadDepartment of Orthopedics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.
Jonas WidmerSpine Biomechanics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVertebropexy (VPX) is a purely tendon-based fixation technique of the lumbar spine. It stabilizes the segment in flexion, without immobilizing it in other directions, and therefore might biomechanically address some shortcomings of both spinal fusion and decompression-only surgery. This newly developed cyclic testing setup evaluates the ability of VPX to maintain flexion restriction under long-term biomechanical loading.

methodsFive spinal segments of three cadaveric human lumbar spines were selected for testing. VPX was performed using a human peroneus longus tendon allograft, looped twice around the spinous processes and secured with a Prusik knot. Each segment underwent load-controlled flexion-extension (FE) testing in five conditions: native (intact), after decompression (deco-pre, bilateral laminorecessotomy), after VPX (VPX-pre), after long-term cyclic simulation (VPX-post), and after removal of VPX (deco-post). Long-term behavior was simulated using the Dynamic Spine Simulator (DSS), applying 46,800 cycles in the three principal motion directions (FE, lateral bending (LB), axial rotation (AR)).

resultsCompared to the paired decompressed state (deco-pre), median flexion immediately after VPX decreased to 0.5% [25th-75th percentile: - 26.3% to 12.9%]. Following the controlled cyclic durability simulation, VPX limited median flexion to 40.0% [4.2%-54.0%] relative to its decompressed state (deco post).

conclusionsThis cadaveric proof-of-concept study demonstrates that VPX maintains stabilizing function following cyclic loading. Immediately after decompression, pre-tensioning effectively restricts flexion. Following controlled cyclic durability simulation, this restriction partially attenuates while preserving a net stabilizing effect relative to the decompressed state. These findings support VPX as a biomechanically reasonable dynamic ligamentous restraint that warrants further investigation in larger cadaveric samples and ultimately in vivo validation.

Indexed as

Dynamic stabilizationLumbar fusionSpinal stabilizationSpine simulatorTendon biomechanicsVPX

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.