ArticleAesthetic plastic surgery2026
Preexisting Depression or Anxiety is Associated with Increased Wound Complications Following Breast Reduction Surgery: A Real-World Cohort Study.
Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBreast reduction surgery is the primary treatment for macromastia, yet the impact of preexisting anxiety and depressive disorders (ADD) in candidates for this procedure has not been thoroughly investigated. This study aimed to evaluate the association between preexisting ADD and the incidence of both short-term and long-term complications after breast reduction surgery.
methodsThis retrospective cohort study used data obtained from the TriNetX Global Collaborative Network to identify female patients over 18 years who had breast reduction. These patients were divided into two cohorts based on the presence or absence of ADD diagnosis. To reduce baseline differences and balance characteristics of the cohorts, we applied a propensity score matching. The primary objectives were short postoperative complications at 30, 60, and 90 days. Secondary objectives were long-term complications after 1 year.
resultsEach cohort included 15,846 patients after 1:1 PSM analysis. Thirty days after surgery, patients with preexisting ADD were associated with significantly higher risks of seroma (Relative Risk [RR] 1.895, CI 1.43-2.5); hematoma (RR 1.508, CI 1.2-1.88); wound dehiscence (RR 1.33, CI 1.12-1.57); surgical site infection (RR 1.495, CI 1.24-1.79); postoperative opioid use (RR 1.291, CI 1.25-1.34); inpatient hospitalization (RR 1.77, CI 1.505-2.101); readmission (RR 1.857, CI 1.46-2.35); and any surgical site complications (RR 1.358, CI 1.23-1.50) compared to the control cohort. These findings persisted after 60 and 90 days of surgery. Comparable results were noted for long-term outcomes within 1 year of surgery.
conclusionPatients with preexisting anxiety or depression disorders demonstrated higher rates of short-term postoperative outcomes after breast reduction procedure. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
Indexed as
Identifiers
42324397What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.