Evidence map›Paper›PMID 42324319›Full record

ArticleScientific reports2026

Temporal patterns of haemoglobin phenotypes among Nigerian university students based on ten years of surveillance data.

Thomas Olumide Adeleke, Chukwudumebi Placid Ughonu, Efeturi Agelebe, Oludamola Victoria Adeleke, Taiwo Omotayo Dosumu, Dolapo Emmanuel Ajala, Bayonle Ayenigba, Samuel Ademola Adegoke, Tina M Slusher, Alexander A Boucher

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Thomas Olumide AdelekeDepartment of Family Medicine, Bowen University, Iwo, Nigeria. tomolumighty@gmail.com.
Chukwudumebi Placid UghonuBowen University Teaching Hospital, Ogbomoso, Nigeria.
Efeturi AgelebeDepartment of Paediatrics, College of Health Sciences, Bowen University, Iwo, Nigeria.
Oludamola Victoria AdelekeClinical Nurse, Directorate of Health Services, Bowen University, Iwo, Nigeria.
Taiwo Omotayo DosumuDepartment of Maternal and Child Health, Faculty of Nursing, College of Health Sciences, Bowen University, Iwo, Nigeria.
Dolapo Emmanuel AjalaClinical Nurse, Directorate of Health Services, Bowen University, Iwo, Nigeria.
Bayonle AyenigbaLaboratory Unit, Directorate of Health Services, Bowen University, Iwo, Nigeria.
Samuel Ademola AdegokeDepartment of Paediatrics and Child Health, Obafemi Awolowo University, Ile-Ife, Nigeria.
Tina M SlusherDepartment of Paediatrics, University of Minnesota, Minneapolis, MN, USA.
Alexander A BoucherDivision of Hematology, Oncology, and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Haemoglobinopathies remain among the most common monogenic disorders worldwide, with sickle cell disease (SCD) and various forms of thalassemia posing significant challenges to public health systems, particularly in low- and middle-income countries. This study presents a ten-year retrospective analysis of haemoglobin phenotype surveillance data, encompassing multiple regions and demographic strata. This retrospective work was conducted at Bowen University Hospital, Iwo, Osun State, southwestern Nigeria between January 2015 and December 2024. Data were extracted and analyzed using machine learning from 8890 medical records of undergraduate annual phenotype screening spanning ten years (2015-2024). HbAA was the most common genotype at 75.11% (n = 6,677). SCD genotypes (HbSS and HbSC) showed a non-significant downward trend over the ten-year period (slope = - 0.03 percentage points/year; R

Indexed as

Anemia, Sickle CellHemoglobinopathiesHemoglobinsStudentsAdultFemaleGenotypeHumansMaleNigeriaPhenotypePrevalenceRetrospective StudiesUniversitiesYoung AdultHemoglobinsGenotypeHaemoglobinNigeriaSickle cell diseaseSurveillance

Identifiers

PMID42324319
PMCPMC13562755

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.