Evidence map›Paper›PMID 42324309›Full record

ArticleSurgical endoscopy2026

Determining the age cut-off for increased surgical risk after Roux-en-Y gastric bypass in elderly patients: MBSAQIP 2015-2023 database analysis.

Raul Sebastian, Oscar Tuesta, Adrian Riva, Alba Zevallos, Jason Silvers, Gina Adrales, Hien Nguyen, Christina Li, Michael Schweitzer

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Article in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Raul SebastianDepartment of Surgery, The Johns Hopkins University, Baltimore, MD, USA.
Oscar TuestaDepartment of Surgery, Northwest Hospital, 5401 Old Court Road, Randallstown, MD, 21133, USA. oscar.benari@gmail.com.ORCID http://orcid.org/0000-0003-0309-1246
Adrian RivaDepartment of Surgery, Northwest Hospital, 5401 Old Court Road, Randallstown, MD, 21133, USA.
Alba ZevallosDepartment of Surgery, Loma Linda University Medical Center, Loma Linda, CA, USA.
Jason SilversDepartment of Surgery, Northwest Hospital, 5401 Old Court Road, Randallstown, MD, 21133, USA.
Gina AdralesDepartment of Surgery, The Johns Hopkins University, Baltimore, MD, USA.
Hien NguyenDepartment of Surgery, The Johns Hopkins University, Baltimore, MD, USA.
Christina LiDepartment of Surgery, Northwest Hospital, 5401 Old Court Road, Randallstown, MD, 21133, USA.
Michael SchweitzerDepartment of Surgery, The Johns Hopkins University, Baltimore, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe elderly population in the United States is projected to double by 2050, along with obesity prevalence. Despite the increasing number of elderly patients undergoing bariatric surgery, evidence on perioperative safety remains limited and conflicting. Given concerns about higher perioperative morbidity, we compared 30-day outcomes and bariatric-specific complications after Roux-en-Y gastric bypass (RYGB) across age subgroups within the elderly bariatric population.

methodsPatients aged > 60 years who underwent RYGB were identified from the 2015 to 2023 MBSAQIP database. A 1:1 propensity score matching analysis using 22 preoperative characteristics was performed to compare 30-day outcomes between early versus late sexagenarians (60-64 vs. 65-69), early versus late septuagenarians (70-74 vs. 75-79), and late sexagenarians versus early septuagenarians (65-69 vs. 70-74).

resultsWe analyzed 45,775 RYGB patients. Except for Analysis 1, no differences were found in mortality, unplanned ICU admissions, or cardiopulmonary complications. After matching, Analysis 1 (n = 16,273) showed that late sexagenarians had higher rates of mortality, pulmonary complications, unplanned ICU admissions, blood transfusions, readmissions, and non-home discharge. In Analysis 2 (n = 2351; n = 600), late septuagenarians had higher rates of pulmonary complications, conversion to open, and non-home discharge. In Analysis 3 (n = 4307), early septuagenarians had higher rates of venous thromboembolism and non-home discharge.

conclusionsRYGB is safe and feasible across elderly subgroups, with acceptable mortality, unplanned ICU admission, and cardiopulmonary complication rates. However, patients aged > 65 had significantly higher mortality and morbidity, suggesting this age as a threshold for increased perioperative risk. These findings highlight the importance of careful patient selection and preoperative optimization, particularly in patients older than 65 years.

Indexed as

Gastric BypassObesity, MorbidPostoperative ComplicationsAgedAge FactorsDatabases, FactualFemaleHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesRisk AssessmentRisk FactorsUnited StatesBariatric surgeryElderlyOperative riskRoux-en-Y gastric bypass

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.