ArticleContact dermatitis2026
Fragrance and Preservative Contact Allergens in Cosmetic and Household Cleaning Products in Turkey: Variation by Target Population, Product Type and Manufacturing Origin.
Article in Contact dermatitis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundFragrance and preservative chemicals in cosmetic and household cleaning products are recognised causes of allergic contact dermatitis.
objectivesTo identify fragrance and preservative ingredients with potential contact allergenicity in Turkish market products.
methodsLabels of 245 products, including predominantly rinse-off cosmetic products and household cleaning products obtained during on-site visits to chain supermarkets were reviewed. Fragrance and preservative ingredients were scored (0-2) for reported allergen potential and summed as an 'allergen load' per product.
resultsCosmetics had significantly higher number of fragrance ingredients and fragrance loads than cleaning products. The most frequent fragrance substances were linalool, limonene and hexyl cinnamal. Paediatric products contained fewer fragrance and preservative ingredients than adult products. Sodium benzoate, methylisothiazolinone (MI) and methylchloroisothiazolinone (MCI) were the most common preservatives; laundry detergents had the highest preservative load, wet wipes and surface cleaners the lowest. Anti-dandruff shampoos had higher allergen loads than regular shampoos. Fragrance-free/preservative-free claims conflicted with labels in 21.2%. Fragrance and preservative loads were weakly correlated (Spearman's rho = 0.260, p < 0.001).
conclusionsFragrance and preservative allergens are common in cosmetic and cleaning products in Turkey. More frequent MI and MCI in domestic products suggests limited substitution and possible regulatory gaps; anti-dandruff shampoos warrant caution.
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