Evidence map›Paper›PMID 42324097›Full record

ArticleImmunology2026

The Transcription Factor EGR2 Plays a Central Role in the Expansion and Function of TCRαβ

Rujuan Dai, Zhuang Wang, Bettina Heid, Christopher M Reilly, S Ansar Ahmed

Abstract read
In one paragraph

Article in Immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rujuan DaiDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine (VMCVM), Virginia Tech, Blacksburg, Virginia, USA.ORCID https://orcid.org/0000-0002-1074-8974
Zhuang WangDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine (VMCVM), Virginia Tech, Blacksburg, Virginia, USA.
Bettina HeidDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine (VMCVM), Virginia Tech, Blacksburg, Virginia, USA.
Christopher M ReillyDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine (VMCVM), Virginia Tech, Blacksburg, Virginia, USA.
S Ansar AhmedDepartment of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine (VMCVM), Virginia Tech, Blacksburg, Virginia, USA.

Funding

Edward Via College of Osteopathic Medicine (VCOM)-Virginia-Maryland College of Veterinary Medicine (VMCVM) One Health Research Seed 461722VMCVM Intramural Research Competition (IRC) 180472
6 · The paper itself

Abstract

TCRαβ

Indexed as

Early Growth Response Protein 2Lupus Erythematosus, SystemicReceptors, Antigen, T-Cell, alpha-betaT-Lymphocyte SubsetsAnimalsCD8 AntigensFemaleMiceMice, Inbred C57BLMice, Inbred MRL lprMice, KnockoutCD8 AntigensEarly Growth Response Protein 2Egr2 protein, mouseReceptors, Antigen, T-Cell, alpha-beta

Identifiers

PMID42324097
PMCPMC13540510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.