Evidence map›Paper›PMID 42323605›Full record

ArticleJournal of nanobiotechnology2026

Gold nanocluster-complexed dressings for instant closure of bacteria-infected wound.

Shanchen Cai, Wenfu Zheng, Ting Lin, Siyuan Zhang, Lanye He, Mali Zu, Le Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shanchen Cai *Academician Workstation, The Jiangxi Province Key Laboratory for Diagnosis, Treatment, and Rehabilitation of Cancer in Chinese Medicine, Mass Spectrometry Research Center for Diagnosis, Treatment, and Chronic Disease Rehabilitation, Jiangxi University of Chinese Medicine, Nanchang, 330004, Jiangxi, P. R. China.
Wenfu Zheng *School of Nanoscience and Engineering, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Ting LinAcademician Workstation, The Jiangxi Province Key Laboratory for Diagnosis, Treatment, and Rehabilitation of Cancer in Chinese Medicine, Mass Spectrometry Research Center for Diagnosis, Treatment, and Chronic Disease Rehabilitation, Jiangxi University of Chinese Medicine, Nanchang, 330004, Jiangxi, P. R. China.
Siyuan ZhangAcademician Workstation, The Jiangxi Province Key Laboratory for Diagnosis, Treatment, and Rehabilitation of Cancer in Chinese Medicine, Mass Spectrometry Research Center for Diagnosis, Treatment, and Chronic Disease Rehabilitation, Jiangxi University of Chinese Medicine, Nanchang, 330004, Jiangxi, P. R. China.
Lanye HeXiyuan Hospital of China Academy of Chinese Medical Sciences, No. 1 Xiyuancaochang Road, Haidian District, Beijing, 100091, P.R. China.
Mali ZuCAS Key Lab for Biological Effects of Nanomaterials and Nanosafety, National Center for NanoScience and Technology, Beijing, 100190, P. R. China.
Le WangAcademician Workstation, The Jiangxi Province Key Laboratory for Diagnosis, Treatment, and Rehabilitation of Cancer in Chinese Medicine, Mass Spectrometry Research Center for Diagnosis, Treatment, and Chronic Disease Rehabilitation, Jiangxi University of Chinese Medicine, Nanchang, 330004, Jiangxi, P. R. China. wangle@jxutcm.edu.cn.

Funding

National Natural Science Foundation of China 22304065National Natural Science Foundation of China U23A20686Natural Science Foundation of Jiangxi Province of China 20242BAB20088Project of Academic and Technical Leaders in Major Disciplines in Jiangxi Province 20243BCE51158
6 · The paper itself

Abstract

Rapid closure is crucial for effective wound healing. However, current wound dressings often fall short in this aspect. Herein, we present a light-responsive wound dressing (A@MC) composed of a heat-curable methyl cellulose (MC) hydrogel and aminophenylboronic acid (ABA)-modified gold nanoclusters (AGNCs). The A@MC is injectable and can conform, connect, and adhere to wounds of irregular shapes before gelation. Upon near-infrared (NIR) light irradiation, the photothermal effect of the AGNCs triggers an instant gelation and contraction of the dressing and simultaneously a sharp shrinkage of the wound. It achieves a shrinkage rate up to 46% within 5 min for bacteria-infected wound in mice. Moreover, the contraction of A@MC can achieve a rapid release (16%, 5 min) of the AGNCs, which can bind to bacteria through ABA-lipopolysaccharide (LPS) interaction, displaying a targeted antibacterial therapy. The A@MC realizes an accelerated healing (complete healing within 14 days) of multidrug-resistant Pseudomonas aeruginosa (P.a)-infected wounds.

Indexed as

Anti-Bacterial AgentsBandagesGoldMetal NanoparticlesWound HealingWound InfectionAnimalsHydrogelsMicePseudomonas aeruginosaPseudomonas InfectionsAnti-Bacterial AgentsGoldHydrogelsAntibacterial effectGelationGold nanoclustersHydrogelPhotothermalRapid wound closure

Identifiers

PMID42323605
PMCPMC13536748

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.