ArticleBMC nephrology2026
Sex differences in peritoneal dialysis duration and management among Japanese patients: a nationwide registry analysis.
Article in BMC nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeritoneal dialysis (PD) duration is limited worldwide by PD-related infections and difficulties in fluid and solute management. Sex-associated differences in PD duration among Japanese patients have not been well characterized. We examined sex-associated differences in clinical characteristics, PD duration, and PD-related outcomes using a nationwide Japanese registry.
methodsWe retrospectively analyzed annual aggregated data of adult Japanese patients on PD extracted from the Japanese Society for Dialysis Therapy Renal Data Registry (2014-2023; cumulative 74,274 patients). Because the extract contained annual aggregated statistics rather than individual-level data, analyses were descriptive and based on within-year cross-sectional comparisons. We compared male and female patients regarding PD duration, fluid management, solute clearance, and PD-related infections, and performed diabetes-stratified analyses, a descriptive temporal trend analysis, and body-composition-corrected sensitivity analyses for fluid output indices.
resultsFemale patients consistently had longer mean PD duration than male patients in every year from 2014 to 2023; in 2023, the difference was 4.80 months (95% confidence interval, 3.10 to 6.50), and the 10-year sample size-weighted mean was 28.59 months in male versus 34.73 months in female patients. Female patients also had higher registry-reported total Kt/V (weighted mean, 1.90 vs. 1.76) and a higher total output (urine output + PD ultrafiltration volume) / body weight ratio, calculated as a ratio of annual means (24.0 vs. 21.5 mL/kg/day). The sex difference in PD duration persisted in both diabetic and non-diabetic strata.
conclusionIn this nationwide descriptive analysis, female patients on PD in Japan had longer registry-recorded PD duration and higher registry-reported indices of fluid and solute management than male patients, with differences persisting across diabetes strata. However, because the analyses were based on aggregated registry data with substantial, potentially non-random missingness and without patient-level adjustment, causal inference is not possible, and the findings should be interpreted strictly as registry-level descriptive associations rather than patient-level survival or technique-failure differences.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.