Evidence map›Paper›PMID 42323510›Full record

ArticleSpine deformity2026

Comparative morbidity and outcomes for adult spinal deformity corrections spanning C2-pelvis compared to T4-pelvis: a propensity score-matched analysis.

Alexander T Yahanda, Karan Joseph, Tim T Bui, Nicholas A Pallotta, Brian J Neuman, Jacob K Greenberg, Daniel Hafez, Wilson Z Ray, Munish C Gupta, Camilo A Molina

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Article in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Alexander T YahandaDepartment of Neurological Surgery, Washington University School of Medicine in St. Louis, 660 S Euclid Ave, CB 8057, St. Louis, MO, 63110, USA. ayahanda@wustl.edu.ORCID http://orcid.org/0000-0003-3630-1166
Karan JosephDepartment of Neurological Surgery, Washington University School of Medicine in St. Louis, 660 S Euclid Ave, CB 8057, St. Louis, MO, 63110, USA.
Tim T BuiDepartment of Neurological Surgery, Washington University School of Medicine in St. Louis, 660 S Euclid Ave, CB 8057, St. Louis, MO, 63110, USA.
Nicholas A PallottaDepartment of Orthopedic Surgery, Washington University School of Medicine in St. Louis, 660 S Euclid Ave, St. Louis, MO, 63110, USA.
Brian J NeumanDepartment of Orthopedic Surgery, Washington University School of Medicine in St. Louis, 660 S Euclid Ave, St. Louis, MO, 63110, USA.
Jacob K GreenbergDepartment of Neurological Surgery, Washington University School of Medicine in St. Louis, 660 S Euclid Ave, CB 8057, St. Louis, MO, 63110, USA.
Daniel HafezDepartment of Neurological Surgery, Washington University School of Medicine in St. Louis, 660 S Euclid Ave, CB 8057, St. Louis, MO, 63110, USA.
Wilson Z RayDepartment of Neurological Surgery, Washington University School of Medicine in St. Louis, 660 S Euclid Ave, CB 8057, St. Louis, MO, 63110, USA.
Munish C GuptaDepartment of Orthopedic Surgery, Washington University School of Medicine in St. Louis, 660 S Euclid Ave, St. Louis, MO, 63110, USA.
Camilo A MolinaDepartment of Neurological Surgery, Washington University School of Medicine in St. Louis, 660 S Euclid Ave, CB 8057, St. Louis, MO, 63110, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSurgical corrections for adult spinal deformity (ASD) often extend from T4-pelvis. Certain patients may require fusion from C2-pelvis. Comparisons are necessary to guide surgical decision-making, particularly for frailer patients with multiple comorbidities. This study analyzed the additional morbidity incurred by proceeding with fusion to the upper cervical spine (i.e., C2) versus to T4.

methodsThis was a retrospective analysis comparing C2-pelvis versus T4-pelvis fusions for ASD. Patients were propensity-matched in a 1:4 ratio based on age, sex, ASA score, BMI, smoking, diabetes, and use of 3-column osteotomy. Outcomes included postoperative complications, hospital/ICU length-of-stay (LOS), time-to-ambulation, 30- and 90-day readmission rates, reoperations, and overall survival (OS).

results80 patients (16 C2-pelvis, 64 T4-pelvis) were analyzed. All patients had ASA scores ≥ 3. C2-pelvis yielded higher complication rates (100% C2-pelvis vs. 68.7% T4-pelvis; p = 0.008) and number of complications per patient (3.2 ± 2.2 C2-pelvis vs. 1.3 ± 1.6 T4-pelvis; p = 0.004). For specific complications, C2-pelvis more often yielded prolonged hypotension requiring vasopressors (p < 0.001), psychiatric complications (p = 0.04), and delirium (p = 0.04). Hospital LOS was similar between cohorts (p = 0.33), but ICU LOS (p = 0.02) and time-to-ambulation (p = 0.046) were longer after C2-pelvis. C2-pelvis had higher readmission rates within 30 (p = 0.001) and 90 (p = 0.001) days. OS was shorter after C2-pelvis (24.4 ± 2.8 months vs. 68.5 ± 4.2 months for T4-pelvis; p < 0.001).

conclusionsC2-pelvis fusions for ASD yield significantly higher rates/numbers of complications, longer ICU LOS, longer time-to-ambulation, higher readmission rates, and shorter OS than T4-pelvis fusions, even among patients of similar age and systemic disease/comorbidities. Greater follow-up and numbers of C2-pelvis patients are required for more definitive outcome comparisons.

Indexed as

Adult spinal deformityC2-pelvisPostoperative complicationsPostoperative outcomesSpinal deformitySpinal fusionT4-pelvis

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.