Evidence map›Paper›PMID 42323486›Full record

ArticlePediatric research2026

Life-course brain health intervention choices are improved by applying knowledge of metaplasticity.

Mark S Scher

Abstract readComment
PubMed Publisher
In one paragraph

Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Mark S ScherEmeritus Scholar and Professor Pediatrics and Neurology Case Western Reserve University School of Medicine, Cleveland, OH, USA. Mark.S.Scher@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This commentary discusses a recently published review of metaplasticity. This neuroscientific concept strengthens fetal-neonatal neurology principles and practice to promote life-course brain health. Recommended applications during interdisciplinary training will be re-enforced with career-long experiences. Greater understanding will contribute to development of brain health capital strategies that more effectively apply diagnostic and therapeutic advances. Knowledge and practice of reproductive and pregnancy health for women and their partners will improve prenatal and neonatal proactive and reactive neuroprotective intervention choices, adjusted over the lifespan to maximize intergenerational benefits.

Identifiers

PMID42323486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.