ArticleAdvanced materials (Deerfield Beach, Fla.)2026
Self-Adaptive Charge Transfer States in Aqueous Solutions Promote Fast Intersystem Crossing in a Photosensitizer for Tumor Inhibition.
Ran Wang, Xiang Xia, Zongwei Zhang, Tian Qiu, Wangna Tang, Danhong Zhou, Xiaolong Zeng, Jiangli Fan, Xiaojun Peng, Wen Sun
Abstract read
In one paragraphArticle in Advanced materials (Deerfield Beach, Fla.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Ran WangState Key Laboratory of Fine Chemicals, Frontiers Science Center for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian, China.
Xiang XiaState Key Laboratory of Fine Chemicals, Frontiers Science Center for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian, China.ORCID https://orcid.org/0009-0005-3703-0566 Zongwei ZhangState Key Laboratory of Fine Chemicals, Frontiers Science Center for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian, China.
Tian QiuState Key Laboratory of Fine Chemicals, Frontiers Science Center for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian, China.
Wangna TangState Key Laboratory of Fine Chemicals, Frontiers Science Center for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian, China.
Danhong ZhouState Key Laboratory of Fine Chemicals, Frontiers Science Center for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian, China.
Xiaolong ZengState Key Laboratory of Fine Chemicals, Frontiers Science Center for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian, China.
Jiangli FanState Key Laboratory of Fine Chemicals, Frontiers Science Center for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian, China.ORCID https://orcid.org/0000-0003-4962-5186 Xiaojun PengState Key Laboratory of Fine Chemicals, Frontiers Science Center for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian, China.ORCID https://orcid.org/0000-0002-8806-322X Funding
Fundamental Research Fundamental Funds for the Central Universities DUT22LAB601Fundamental Research Fundamental Funds for the Central Universities DUT25YG270Liaoning Province Science and Technology Plan Joint Program 2024JH2/102600030National Science Foundation of China 22208046National Science Foundation of China 22408042National Science Foundation of China 22478060"Oncology+" Open project of Liaoning Cancer Hospital 2024-ZLKF-37Postdoctoral Fellowship Program of CPSF GZC20230353Xingliao Talent Program XLYC2203079
6 · The paper itselfAbstract
Although conventional design strategies of photosensitizers (PSs) have enabled control of their excited-state evolution in organic solvents, their distinct photophysical evolution pathways in aqueous solutions severely reduce their intersystem crossing (ISC) rates and reactive oxygen species (ROS) yields. Thus, the design of high-performance PSs with high ISC rates and ROS yields in aqueous solutions remains a challenge for photodynamic therapy (PDT). In this study, we utilized the ability of aqueous solvents to promote charge transfer to construct Cy5-PCZ, a PS that can self-adaptively generate charge transfer singlet states (
Indexed as
Antineoplastic AgentsPhotosensitizing AgentsAnimalsApoptosisCarbocyaninesCell Line, TumorHumansMicePhotochemotherapyReactive Oxygen SpeciesSolutionsWaterAntineoplastic AgentsCarbocyaninesPhotosensitizing AgentsReactive Oxygen SpeciesSolutionsWatercharge transfer statesintersystem crossingphotodynamic therapyphotosensitizersreactive oxygen species
Identifiers
PMID42322596
PMCPMC13411034
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