ArticlePediatric surgery international2026
Clinical characteristics and predictors for the presence of pediatric intussusception secondary to pathological lead points.
Article in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo analyze the clinical characteristics and identify independent predictors of intussusception secondary to pathological lead points (PLPs).
methodsWe conducted a retrospective study of children surgically treated for intussusception between 2010 and 2025. Patients were categorized into PLPs and non-PLPs groups. Demographic, clinical, laboratory, imaging, surgical, and pathological data were compared between the groups.
resultsOf 575 children included, 126 (21.9%) had PLPs and 449 (78.1%) were idiopathic. PLPs encompassed a range of etiologies, including Meckel's diverticulum, intestinal duplications, polyps, tumors, and inflammatory conditions. Multivariable logistic regression identified seven independent predictors: older age (OR = 1.023, 95% CI: 1.014-1.032; p < 0.001), the absence of hematochezia (OR = 0.472, 95% CI: 0.268-0.832; p = 0.009), the absence of vomiting (OR = 0.480, 95% CI: 0.242-0.954; p = 0.036), recurrence (OR = 2.313, 95% CI: 1.185-4.513; p = 0.014), small-intestinal intussusception (OR = 2.505, 95% CI: 1.370-4.581; p = 0.003), elevated thrombocytocrit (PCT) (OR = 23.850, 95% CI: 4.902-116.014; p < 0.001), and the presence of ascites (OR = 2.002, 95% CI: 1.209-3.315; p = 0.007).
conclusionsOlder age, hematochezia, vomitus, recurrence intussusception, small-intestinal intussusception, thrombocytocrit and ascites are independent predictors of PLPs and may aid in risk stratification and guide the decision for surgical intervention.
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