Evidence map›Paper›PMID 42322306›Full record

ReviewDiagnostic cytopathology2026

Cytological Features of Clear Cell Sarcoma in Exfoliative and Effusion Cytology Specimen-A Case Report and Literature Review.

William H Wu, Joanna K M Ng, Joshua J X Li

Abstract readCase ReportsReview
In one paragraph

Review in Diagnostic cytopathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

William H WuDepartment of Pathology, School of Clinical Medicine, the University of Hong Kong, Pokfulam, Hong Kong.ORCID https://orcid.org/0009-0000-4584-220X
Joanna K M NgDepartment of Pathology, School of Clinical Medicine, the University of Hong Kong, Pokfulam, Hong Kong.ORCID https://orcid.org/0000-0002-0840-4718
Joshua J X LiDepartment of Pathology, School of Clinical Medicine, the University of Hong Kong, Pokfulam, Hong Kong.ORCID https://orcid.org/0000-0003-2425-0314

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clear cell sarcoma of soft tissue (CCSST) with malignant effusion is a rare yet clinically aggressive appearance, which may pose a diagnostic pitfall with its overlapping cytomorphologic features with metastatic melanoma and carcinoma. In this article, we reported a case with metastatic clear cell sarcoma of soft tissue with positive cytological findings in the sputum, as well as the peritoneal fluid and pericardial fluid. The cytological findings were compared and contrasted with cases reported in the literature. Malignant effusion cytology, variable positivity of melanocytic immunocytochemistry markers (namely S100, SOX10, Melan-A, HMB-45) and confirmatory molecular pathology techniques (e.g., detection of underlying EWSR1 gene rearrangement by fluorescent in situ hybridization or by reverse transcription polymerase chain reaction for EWSR1-ATF1 gene fusion) formed the key diagnostic approach of this entity.

Indexed as

Sarcoma, Clear CellBiomarkers, TumorHumansMaleMiddle AgedPericardial EffusionBiomarkers, Tumorclear cell sarcomacytologyeffusionexfoliation

Identifiers

PMID42322306
PMCPMC13532602

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.