Evidence map›Paper›PMID 42321841›Full record

ArticleJournal of biomedical semantics2026

FAIR in practice: minimum metadata schema for bioinformatics analytics by machines.

Daphne Wijnbergen, Núria Queralt-Rosinach, Valérie Barbié, Emma Verkinderen, Nirupama Benis, Annika Jacobsen, Peter A C 't Hoen, Claudio Carta, Marco Roos, Eleni Mina

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Article in Journal of biomedical semantics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Daphne Wijnbergen *Leiden University Medical Center, Leiden, The Netherlands. d.wijnbergen@lumc.nl.
Núria Queralt-Rosinach *Leiden University Medical Center, Leiden, The Netherlands.
Valérie BarbiéSwiss Institute of Bioinformatics, Geneva, Switzerland.
Emma VerkinderenUniversité Libre de Bruxelles, Brussels, Belgium.
Nirupama BenisAmsterdam UMC Location University of Amsterdam, Amsterdam, The Netherlands.
Annika JacobsenLeiden University Medical Center, Leiden, The Netherlands.
Peter A C 't HoenRadboud University Medical Center, Nijmegen, The Netherlands.
Claudio CartaIstituto Superiore di Sanità, Rome, Italy.
Marco RoosLeiden University Medical Center, Leiden, The Netherlands.
Eleni MinaLeiden University Medical Center, Leiden, The Netherlands.

Funding

European Union's Horizon 2020 research and innovation programme 825575European Union's Horizon Europe research and innovation programme 101156595Innovative Health Initiative Joint Undertaking (IHI JU) 101132943Innovative Health Initiative Joint Undertaking (IHI JU) 101172872UK Research and Innovation (UKRI) 10105921
6 · The paper itself

Abstract

backgroundOne pillar of FAIR principles adoption is Reusability by machines to enable for example more efficient data analytics in fields such as Bioinformatics. However, it is not clear to what extent current metadata exposed by datasets and tools in common repositories enable this. In practice, metadata often lacks in machine actionability due to incomplete standardised metadata and lack of ontological descriptions.

resultsIn this work, we identified minimal metadata that is needed to improve the machine actionability of bioinformatics tools and proposed a schema to address current limitations. The schema consists of metadata properties for the identification, selection, validation, and execution of tools. We also aligned this metadata to the metadata of datasets, in order to improve their integration for analytics by machines.

conclusionsThe identified minimal metadata improves the machine actionability of tools and data, and can be incorporated into platforms for tool and data sharing, and in FAIR infrastructures.

Indexed as

Computational BiologyMetadataData AnalyticsBioinformaticsFAIRMachine-actionabilityMetadata

Identifiers

PMID42321841
PMCPMC13281499

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.