Evidence map›Paper›PMID 42321791›Full record

ArticleRadiation oncology (London, England)2026

Intrafractional variation of breath-hold radiotherapy for gastric lymphoma.

Shuhei Miyazaki, Ryo Toya, Yutaro Tasaki, Mika Nakatake, Akiko Egawa, Daisuke Nakamura, Jun Nakagawa, Takaaki Nakamura, Takuya Yamazaki

Abstract read
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In one paragraph

Article in Radiation oncology (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shuhei MiyazakiDepartment of Radiological Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Ryo ToyaDepartment of Radiological Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. toya@nagasaki-u.ac.jp.ORCID http://orcid.org/0000-0001-9764-5718
Yutaro TasakiDepartment of Radiological Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Mika NakatakeDepartment of Radiological Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Akiko EgawaDepartment of Radiological Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Daisuke NakamuraDepartment of Radiological Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Jun NakagawaDepartment of Radiological Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Takaaki NakamuraDepartment of Radiological Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Takuya YamazakiDepartment of Radiological Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadiotherapy (RT) for localized gastric lymphoma requires large margins due to respiratory motion. Breath-hold RT is performed to reduce respiratory motion. However, intrafractional variation (IV) during breath-hold RT has not been fully evaluated. We quantitatively evaluated IV during breath-hold RT for gastric lymphoma.

methodsTwenty-one patients with localized gastric lymphoma underwent breath-hold RT between 2013 and 2023. They underwent 3-4 computed tomography (CT) simulation scans with breath-holding during the end-expiratory phase of the respiratory cycle. Two radiation oncologists jointly defined a clinical target volume (CTV), and the sum of all CTVs (CTV

resultsMean CTV was 209 ± 86 cm³, with all patients showing maximum volumetric changes within 4% of the mean CTV. Mean CTV center displacement from the mean center position was 1.6 ± 1.0 mm (AP), 1.1 ± 0.9 mm (LR), and 2.1 ± 1.6 mm (SI). Mean displacement of each CTV border from the CTV

conclusionsBreath-hold RT for gastric lymphoma achieves a small IV, but significantly larger IVs were observed in CT1 than CT2-4 and in elderly patients. Multiple breath-hold CT scans at simulation are recommended to assess the IV, and application of breath-hold RT in elderly patients should be individualized.

Indexed as

Breath HoldingRadiotherapy Planning, Computer-AssistedStomach NeoplasmsAdultAgedAged, 80 and overDose Fractionation, RadiationFemaleHumansMaleMiddle AgedRadiotherapy, Intensity-ModulatedRetrospective StudiesTomography, X-Ray ComputedBreath-hold radiotherapyGastric lymphomaIntrafractional variationRadiotherapyRespiratory motionTarget volume

Identifiers

PMID42321791
PMCPMC13536849

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.