Evidence map›Paper›PMID 42321686›Full record

ArticleBMC geriatrics2026

A retrospective study on the application of unilateral epidural anesthesia in older patients with hip fracture.

Peng Liu, Xin Shi, Jiang Hu, Jiabing Li, Weimin Liang, Weizhe Jiang, Jingbo Zhao

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Article in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Peng LiuDepartment of Orthopedic Surgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Xin ShiDepartment of Anesthesiology, Bazhou District People's Hospital, Bazhong, Sichuan, China.
Jiang HuDepartment of Orthopedic Surgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Jiabing LiDepartment of Orthopedic Surgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Weimin LiangDepartment of Orthopedic Surgery, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, China.
Weizhe JiangDepartment of Anesthesiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No. 32 West Second Section, First Ring Road, Chengdu, 610072, China.
Jingbo ZhaoDepartment of Anesthesiology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, No. 32 West Second Section, First Ring Road, Chengdu, 610072, China. z02j06bo@163.com.ORCID 0000-0002-5412-1137

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe analyzed data from older patients (≥ 65 years) with hip fractures who underwent surgical treatment with unilateral epidural anesthesia (UEA) or combined spinal-epidural anesthesia (CSEA) to compare perioperative outcomes between the two anesthetic techniques. PATIENTS AND

methodsOne hundred and six older patients with hip fractures who underwent surgery were retrospectively analyzed and stratified into UEA and CSEA groups. The clinical variables investigated included ephedrine use, preanesthetic and postanesthetic hemodynamic heart rate, oxygen saturation changes at 5, 10, 15, and 20 min, complications, duration of hospital stay, mortality, and lower limb function.

resultsThe duration of anesthesia in the CSEA group was shorter than in the UEA group (P < 0.05). There were no significant differences in sensory block duration or recovery (P > 0.05). Systolic blood pressure was significantly higher in the UEA group than in the CSEA group at all post‑anesthesia time points (5, 10, 15, and 20 min) (all P < 0.05). There were no significant differences in vasopressor use, hypotension, urinary retention, or phantom limb sensations between the two groups (all adjusted P > 0.05). No significant differences were found in sedative use, postoperative complications, duration of hospital stay, critical care admission, mortality, or lower limb function (P > 0.05).

conclusionCompared with CSEA, UEA was associated with more stable hemodynamics. Despite a longer induction time, UEA represents a viable anesthetic option for older patients with hip fractures. These findings are exploratory and hypothesis-generating due to the retrospective, non-randomized design. Further prospective studies are needed to confirm these results.

Indexed as

Anesthesia, EpiduralAnesthesia, SpinalHip FracturesAgedAged, 80 and overFemaleGeriatric AnesthesiaHumansMaleRetrospective StudiesCombined spinal-epidural anesthesiaHemodynamic stabilityHip fractureOlder patientsUnilateral epidural anesthesia

Identifiers

PMID42321686
PMCPMC13531904

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.