Evidence map›Paper›PMID 42321649›Full record

ArticleBMC infectious diseases2026

Uncovering COVID-19 vaccine acceptance and intent in 15 developing countries: a multi-level, clustered analysis of six months of repeated, cross-sectional data.

Cristina A Smith, Daniel Handysides, Alan Cupino, Anna Nelson, W Lawrence Beeson

Abstract read
In one paragraph

Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cristina A SmithSchool of Public Health, Loma Linda University, 11139 Anderson St, Loma Linda, CA, USA. csmith6788@outlook.com.ORCID http://orcid.org/0000-0003-2584-6160
Daniel HandysidesSchool of Public Health, Loma Linda University, 11139 Anderson St, Loma Linda, CA, USA.ORCID http://orcid.org/0000-0003-1052-3115
Alan CupinoSchool of Public Health, Loma Linda University, 11139 Anderson St, Loma Linda, CA, USA.ORCID http://orcid.org/0000-0003-3323-0040
Anna NelsonSchool of Public Health, Loma Linda University, 11139 Anderson St, Loma Linda, CA, USA.ORCID http://orcid.org/0000-0003-0683-8122
W Lawrence BeesonSchool of Public Health, Loma Linda University, 11139 Anderson St, Loma Linda, CA, USA.ORCID http://orcid.org/0000-0002-7415-6046

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 vaccination hesitancy is antithetical to preventing communicable disease. The study's aim was to determine social ecological factors associated with vaccination acceptance / intent in select developing countries.

methodsTo examine vaccine acceptance / intent in fifteen developing countries, data was sourced from the Global COVID-19 Trends and Impacts Survey and analyzed with a multi-level, clustered, cross-sectional design. Weighted Generalized Additive Modeling (GAM) with 1,000 stratified cluster bootstraps mitigated intra-cluster correlation and temporal dependencies.

resultsStatistically significant linear variables included those age 55 + (OR = 1.204, 95% CI [1.095, 1.324], p < 0.001) and identification as female (OR = 1.538, 95% CI [1.448, 1.630], p < 0.001), which were responsible for increased odds of vaccine acceptance / intent. Percent Fear of Vaccine Side Effects (EDF = 2.50, p < 0.001) demonstrated a nonlinear decline in vaccine acceptance / intent. Time (Month) (EDF = 1.94, p < 0.001) was associated with a concave parabolic trend. Cultural Principal Components (PCs) 1-3, respectively, (EDF = 3.97, p < 0.001). EDF = 4.87, p < 0.001), and (EDF = 4.95, p < 0.001) demonstrated oscillating patterns of vaccine acceptance / intent depending upon cultural score direction and magnitude. All PCs demonstrated lower levels of vaccination acceptance / intent with no definitive cultural leaning. There was, however, a push-pull effect among all three dimensions, demonstrating PCs either drove or suppressed vaccination acceptance / intent.

conclusionsVaccine decision-making complexities are associated with cultural and individual influences. Such findings could inform future vaccine campaign strategies.

Indexed as

COVID-19COVID-19 VaccinesPatient Acceptance of Health CareVaccinationVaccination HesitancyAdultAgedCluster AnalysisCross-Sectional StudiesDeveloping CountriesFemaleHumansIntentionMaleMiddle AgedSARS-CoV-2COVID-19 VaccinesCOVID-19CultureSEMVaccination

Identifiers

PMID42321649
PMCPMC13528076

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.