Evidence map›Paper›PMID 42321601›Full record

ArticleCancer medicine2026

Perceived Discrimination and Healthcare System Trust as Barriers to Survivorship Care in Endometrial Cancer.

Jordyn A Brown, Mya L Roberson, Jennifer Richmond, Chantel L Martin, Ganga S Bey, Marc Peterson, Jamie Hunter, Shawn Smith, Stephenie Black-Grant, Victoria L Bae-Jump and 2 more

Abstract read
In one paragraph

Article in Cancer medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jordyn A BrownDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0003-3802-0667
Mya L RobersonDepartment of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0002-9908-910X
Jennifer RichmondDepartment of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
Chantel L MartinDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Ganga S BeyDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Marc PetersonDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Jamie HunterLineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, USA.
Shawn SmithEndometrial Cancer Action Network for African Americans, Seattle, Washington, USA.
Stephenie Black-GrantEndometrial Cancer Action Network for African Americans, Seattle, Washington, USA.
Victoria L Bae-JumpLineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, USA.
Andrew F OlshanDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Hazel B NicholsDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Deborah F. Tate · 1985 to 2026
$201.5M
Cancer Care Quality Training ProgramT32CA116339 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ETHAN M. BASCH, Stephanie Brooke Wheeler · 2018 to 2026
$3.0M
The Carolina Endometrial Cancer Study: A population-based survivor cohortU01CA281026 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Hazel B Nichols · 2024 to 2026
$1.9M
NCI NIH HHS P30CA016086NCI NIH HHS T32 CA116339NCI NIH HHS T32CA116339NCI NIH HHS U01CA281026University Cancer Research Fund of North Carolina
6 · The paper itself

Abstract

backgroundPerceived discrimination can undermine healthcare system trust and contribute to medical mistrust, creating barriers to effective survivorship care. Endometrial cancer survivors, who experience intersecting social, reproductive, and aging-related challenges, remain understudied, and population-level evidence on the relationship between discrimination and medical mistrust in this group is limited.

methodsWe analyzed enrollment survey data from the population-based Carolina Endometrial Cancer Study. Perceived discrimination was measured using the 9-item Everyday Discrimination Scale, categorized into tertiles (low, moderate, high). Medical mistrust was assessed using the 7-item Medical Mistrust Index (MMI), dichotomized as ≥ 1 item endorsed. Modified Poisson regression models estimated adjusted prevalence ratios (aPRs) and 95% confidence intervals (CIs), adjusting for age at diagnosis, region, education, and caregiving support. Analyses were conducted overall and stratified by race, education, and geography, with sensitivity analyses of frequency- and chronicity-based discrimination measures.

resultsAmong 907 survivors (35% Black, mean age 60.9 years), nearly half reported moderate or high perceived discrimination, and more than 80% endorsed ≥ 1 MMI item. Compared with low discrimination, moderate (aPR = 1.20, 95% CI: 1.12-1.30) and high discrimination (aPR = 1.26, 95% CI: 1.17-1.34) were associated with a higher prevalence of mistrust. Associations were consistent across racial, educational, and geographic subgroups. Sensitivity analyses confirmed that both the frequency and intensity of discrimination were positively associated with mistrust.

conclusionPerceived discrimination was common and strongly associated with mistrust among endometrial cancer survivors. Our findings highlight the need for culturally responsive survivorship care and equity-focused interventions to strengthen trust and engagement.

Indexed as

Cancer SurvivorsEndometrial NeoplasmsTrustAgedFemaleHumansMiddle AgedSurvivorshipcancer survivorshipendometrial cancerhealthcare equityhealth disparitiesmedical mistrustperceived discriminationsurvivorship care

Identifiers

PMID42321601
PMCPMC13282185

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.