Evidence map›Paper›PMID 42321560›Full record

ArticleNature immunology2026

Runx-CBFβ regulates the development of tolerogenic Thetis cells.

Chihiro Ogawa, Chengcheng Zou, Yoselin A Paucar Iza, Motoi Yamashita, Tyler Park, Junji Harada, Naoko Satoh-Takayama, Masahiko Kuroda, Chrysothemis C Brown, Ichiro Taniuchi

Abstract read
In one paragraph

Article in Nature immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. RORγtScience immunology · 2026
    Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Chihiro Ogawa *Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.ORCID http://orcid.org/0009-0008-6915-0062
Chengcheng Zou *Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.ORCID http://orcid.org/0000-0003-4802-723X
Yoselin A Paucar IzaImmunology and Microbial Pathogenesis Program, Weill Cornell Medicine Graduate School of Medical Sciences, New York, NY, USA.
Motoi YamashitaLaboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.ORCID http://orcid.org/0000-0002-9814-1033
Tyler ParkComputational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID http://orcid.org/0000-0003-1246-1544
Junji HaradaLaboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.
Naoko Satoh-TakayamaPrecision Immune Regulation, RIKEN ECL Research Unit, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan.ORCID http://orcid.org/0000-0002-7360-5882
Masahiko KurodaDepartment of Molecular Pathology, Tokyo Medical University, Tokyo, Japan.ORCID http://orcid.org/0000-0001-7052-4289
Chrysothemis C BrownImmunology and Microbial Pathogenesis Program, Weill Cornell Medicine Graduate School of Medical Sciences, New York, NY, USA.ORCID http://orcid.org/0000-0002-5834-926X
Ichiro TaniuchiLaboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Japan. ichiro.taniuchi@riken.jp.ORCID http://orcid.org/0000-0002-9853-9068

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Acceptance of non-self: Decoding intestinal immune tolerance during early lifeDP2AI171116 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI Chrysothemis Brown · 2022 to 2026
$2.7M
MEXT | Japan Society for the Promotion of Science (JSPS) 17H04090MEXT | Japan Society for the Promotion of Science (JSPS) 19H05747MEXT | Japan Society for the Promotion of Science (JSPS) 24K10277MEXT | Japan Society for the Promotion of Science (JSPS) 26H02420NCI NIH HHS P30 CA008748NIAID NIH HHS DP2 AI171116
6 · The paper itself

Abstract

Peripherally induced regulatory T (pT

Indexed as

Core Binding Factor Alpha 2 SubunitCore Binding Factor Alpha 3 SubunitCore Binding Factor beta SubunitImmune ToleranceT-Lymphocytes, RegulatoryT-Lymphocyte SubsetsAnimalsCD11c AntigenCell DifferentiationMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicNuclear Receptor Subfamily 1, Group F, Member 3Cbfb protein, mouseCD11c AntigenCore Binding Factor Alpha 2 SubunitCore Binding Factor Alpha 3 SubunitCore Binding Factor beta SubunitNuclear Receptor Subfamily 1, Group F, Member 3Runx1 protein, mouseRunx3 protein, mouse

Identifiers

PMID42321560
PMCPMC13414545

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.