ReviewCommunications biology2026
The electrofluidic brain as a basement layer for neural computation.
Review in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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0 citing papers in PubMed.
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3 authors.
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Abstract
This article reappraises brain function by reconsidering the role of cerebral fluid dynamics in cognition. Tracing a lineage from early modern thinkers like Descartes-who invoked hydraulic metaphors and 'animal spirits'-to J.C. Bose's pioneering studies on electro-mechanical plant physiology, and culminating in contemporary findings on cerebrospinal fluid (CSF), extracellular space (ECS), and neurovascular coupling, we reveal a forgotten yet vital computational substrate. We argue that alongside the well-studied digital operations of neural circuits exists a slower, analog, evolutionarily older layer of electrofluidic computation. This system-comprised of ionic diffusion, convective CSF flow, and vascular modulation-not only supports but dynamically shapes neural activity. The brain emerges as an electromechanical ecology of electric pulses and fluid flows, where the mind is both a pattern of neural activity and a choreography of fluid flows.
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