Evidence map›Paper›PMID 42321248›Full record

ArticleNature communications2026

A cyclin-polarity feedback network ensures healthy cell proliferation.

Landry Peyran, Charles Lefranc, Steven P Gygi, Anne Royou, Derek McCusker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Landry PeyranUniv. Bordeaux, CNRS, Institut de Biochimie et Génétique Cellulaires, UMR 5095; 33077, Bordeaux, France.ORCID http://orcid.org/0009-0008-5149-6815
Charles LefrancUniv. Bordeaux, CNRS, Institut de Biochimie et Génétique Cellulaires, UMR 5095; 33077, Bordeaux, France.
Steven P GygiDepartment of Cell Biology, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-7626-0034
Anne RoyouUniv. Bordeaux, CNRS, Institut de Biochimie et Génétique Cellulaires, UMR 5095; 33077, Bordeaux, France.
Derek McCuskerUniv. Bordeaux, CNRS, Institut de Biochimie et Génétique Cellulaires, UMR 5095; 33077, Bordeaux, France. mccusker@ibgc.cnrs.fr.ORCID http://orcid.org/0000-0003-1455-1711

Funding

Agence Nationale de la Recherche (French National Research Agency) ANR-21-CE13-0045
6 · The paper itself

Abstract

Healthy proliferation requires the coordination of cell cycle progression with cell polarity. In budding yeast, polarity is established when G1-cyclin-Cdc28

Indexed as

Cell PolarityCell ProliferationCyclin G1CyclinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCDC28 Protein Kinase, S cerevisiaecdc42 GTP-Binding Protein, Saccharomyces cerevisiaeCell CycleFeedback, PhysiologicalSignal TransductionCDC28 Protein Kinase, S cerevisiaecdc42 GTP-Binding Protein, Saccharomyces cerevisiaeCyclin G1CyclinsSaccharomyces cerevisiae Proteins

Identifiers

PMID42321248
PMCPMC13434654

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.