Evidence map›Paper›PMID 42321182›Full record

ArticleCell death & disease2026

Frontotemporal dementia associated CHCHD10

Jie Sheng, Jing Yan, Yan Xu, Xingyu Xu, Xuemei Zhang, Anqi Wang, Buhui Liu, Jun Ma, Xiuying Duan, Heng Zhou and 1 more

Abstract read
In one paragraph

Article in Cell death & disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jie Sheng *Jiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Xuzhou, China.
Jing Yan *Jiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Xuzhou, China.
Yan Xu *Jiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Xuzhou, China.
Xingyu XuJiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Xuzhou, China.
Xuemei ZhangJiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Xuzhou, China.
Anqi WangJiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Xuzhou, China.
Buhui LiuJiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Xuzhou, China.
Jun MaThe Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Xiuying DuanSchool of Life Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, China. duanxiuying@sdfmu.edu.cn.ORCID http://orcid.org/0000-0003-3932-0530
Heng ZhouJiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Xuzhou, China. zhouheng@xzhmu.edu.cn.
Wei LiuJiangsu Key Laboratory of Brain Disease Bioinformation, Xuzhou Medical University, Xuzhou, China. wliu@xzhmu.edu.cn.ORCID http://orcid.org/0000-0001-8430-0497

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32200622National Natural Science Foundation of China (National Science Foundation of China) 32300588Natural Science Foundation of Jiangsu Province (Jiangsu Provincial Natural Science Foundation) QN202331, BK20241042Natural Science Foundation of Shandong Province (Shandong Provincial Natural Science Foundation) ZR2025MS323
6 · The paper itself

Abstract

Frontotemporal dementia (FTD), a neurodegenerative disorder characterized by early-onset cognitive decline, includes two major pathologic types: FTD-Tau and FTD-TDP. Coiled-coil-helix-coiled-coil-helix domain containing 10 (CHCHD10) encodes a mitochondrial protein, and the CHCHD10

Indexed as

Frontotemporal DementiaMitochondrial ProteinsMutationrab GTP-Binding Proteinstau ProteinsAnimalsDrosophila melanogasterDrosophila ProteinsHumansMitochondriarab7 GTP-Binding ProteinsCHCHD10 protein, humanDrosophila ProteinsMitochondrial Proteinsrab7 GTP-Binding Proteinsrab7 GTP-binding proteins, humanrab GTP-Binding Proteinstau Proteins

Identifiers

PMID42321182
PMCPMC13526787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.