ArticleThe British journal of radiology2026
Development of in situ dosimetry for FLASH proton radiotherapy via organic scintillating fibers.
Article in The British journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesThis work presents the design, development, and initial proof-of-concept testing of a dosimetry device intended for FLASH radiotherapy.
methodsThe system incorporates organic scintillating fibers coupled to a silicon photomultiplier (SiPM) and an FPGA-based readout, with fiber geometry optimized to minimize perturbations to a clinical proton beam, as confirmed through measurements at the Huntsman Cancer Institute (HCI).
resultsTests using a portable X-ray unit demonstrated a strong correlation between integrated charge and delivered dose (up to ∼35 mrem s-1) and showed that the detector can respond on nanosecond timescales, enabling rapid safety interlock triggering with minimal latency.
conclusionPreliminary proton irradiations at HCI further indicated that the device can resolve individual beam pulses, a capability valuable for both FLASH research and conventional radiotherapy. ADVANCES IN KNOWLEDGE: These results highlight the need for continued refinement of the experimental setup, readout electronics, and detector performance to fully realize real-time, in situ dose and pulse monitoring.
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