Evidence map›Paper›PMID 42319593›Full record

ReviewMolecular biology reports2026

Oleuropein in disease prevention and treatment: A comprehensive review from mechanisms to applications.

Shiyi Yu, Qiugang Zhu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shiyi YuDepartment of Laboratory Medicine, Shangyu People's Hospital of Shaoxing, Shaoxing University, Shaoxing, China.
Qiugang ZhuDepartment of Laboratory Medicine, Shangyu People's Hospital of Shaoxing, Shaoxing University, Shaoxing, China. zqg8091@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The olive family, Oleaceae, is a diverse and widely distributed group of flowering plants that encompasses a rich variety of species with significant ecological, economic, and cultural importance. Oleuropein (OLE) is the most abundant polyphenolic compound in olive leaf extract that exhibits a broad spectrum of pharmacological activities, including antioxidant, anti-inflammatory, anti-tumor, anti-apoptotic, and anti-autophagic effects. These properties render it a promising compound for a wide range of applications. This review summarizes recent research on the potential applications of OLE in disease treatment, with particular emphasis on its underlying mechanisms, including antioxidant activity, regulation of endogenous redox-related enzymes, modulation of key inflammatory signaling pathways, and suppression of pro-inflammatory cytokine production. In addition, this review discusses the latest clinical trials involving OLE and its potential as an adjunct treatment.

Indexed as

IridoidsAnimalsAnti-Inflammatory AgentsAntioxidantsHumansIridoid GlucosidesOleaPlant ExtractsSignal TransductionAnti-Inflammatory AgentsAntioxidantsIridoid GlucosidesIridoidsoleuropeinPlant ExtractsAnti-inflammatoryAntioxidantAnti-tumorNF-κBNrf2Oleuropein

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.