Evidence map›Paper›PMID 42319589›Full record

ArticleAnnals of surgical oncology2026

Distal Resection Margin Collagen Score to Predict Major Low Anterior Resection Syndrome After Neoadjuvant Chemoradiotherapy in Rectal Cancer.

Renyi Zhang, Yongzhen Huang, Xiarong Hu, Yuchen Wang, Wentan Guan, Botao Yan, Biao Zhang, Xunlong Chen, Qiaoling Zheng, Xiaoyu Dong and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Renyi Zhang *Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yongzhen Huang *Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xiarong Hu *Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yuchen Wang *Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Wentan GuanDepartment of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Botao YanDepartment of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Biao ZhangDepartment of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xunlong ChenDepartment of Colorectal Surgery, Fujian Medical University Union Hospital, Gulou District, Fuzhou, China.
Qiaoling ZhengDepartment of Pathology, Fujian Medical University Union Hospital, Fuzhou, China.
Xiaoyu DongDepartment of Colorectal Surgery, Fujian Medical University Union Hospital, Gulou District, Fuzhou, China.
Faisal U L RehmanDepartment of Colorectal Surgery, Fujian Medical University Union Hospital, Gulou District, Fuzhou, China.
Qiuyu ZhangInstitute of Immunotherapy, Fujian Medical University, Fuzhou, China.
Shuangmu ZhuoSchool of Science, Jimei University, Jimei District, Xiamen, China. shuangmuzhuo@jmu.edu.cn.
Jun YanDepartment of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China. yanjunfudan@163.com.

Funding

Clinical Research Program of Nanfang Hospital of Southern Medical University 2022CR003Fujian Province University-industry Cooperation Project 2024Y4018Guangzhou Science and Technology Program 202206010085Joint Funds for the Innovation of Science and Technology, Fujian Province 2024Y9282National Natural Science Foundation of China 82273360President's Fund of Nanfang Hospital of Southern Medical University 2023B053Research Program of Fujian Medical University Union Hospital 2024XH030
6 · The paper itself

Abstract

backgroundLow anterior resection syndrome (LARS) is common after neoadjuvant chemoradiotherapy (nCRT) and sphincter-preserving surgery for rectal cancer and is associated with poor quality of life. However, reliable tools to identify patients at high risk remain limited. This study aims to develop and validate a prediction model for major LARS in patients with rectal cancer after nCRT and sphincter-preserving surgery. PATIENTS AND

methodsA total of 315 consecutive patients between 2019 and 2021 were retrospectively enrolled (training cohort: 213; independent validation cohort: 102). A distal resection margin collagen score (CS

resultsThe CS

conclusionsThe CS

Indexed as

Chemoradiotherapy, AdjuvantCollagenLow Anterior Resection SyndromeMargins of ExcisionNeoadjuvant TherapyNomogramsRectal NeoplasmsAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesCollagenCollagen scoreLow anterior resection syndromeMultiphoton imagingNeoadjuvant chemoradiotherapyNomogramRectal cancer

Identifiers

PMID42319589

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.