Evidence map›Paper›PMID 42319573›Full record

ArticleNeuroscience bulletin2026

Male-Biased Social Deficits in Chd8

Qian Zhang, Yang Qiao, Huixian Li, Jiali Zeng, Jingwen Chen, Hui Zhou, Yuzheng Hu, Jianhong Luo

Abstract read
PubMed Publisher
In one paragraph

Article in Neuroscience bulletin, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qian Zhang *School of Brain Science and Brain Medicine, Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, 310013, China.ORCID https://orcid.org/0009-0008-0790-2257
Yang Qiao *Department of Psychology and Behavioral Sciences, Zhejiang University, Hangzhou, 310058, China.
Huixian LiSchool of Brain Science and Brain Medicine, Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, 310013, China.
Jiali ZengSchool of Brain Science and Brain Medicine, Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, 310013, China.
Jingwen ChenDepartment of Psychology and Behavioral Sciences, Zhejiang University, Hangzhou, 310058, China.
Hui ZhouDepartment of Psychology and Behavioral Sciences, Zhejiang University, Hangzhou, 310058, China.
Yuzheng HuNanhu Brain-computer Interface Institute, Hangzhou, 311100, China. huyuzheng@zju.edu.cn.
Jianhong LuoSchool of Brain Science and Brain Medicine, Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou, 310013, China. luojianhong@zju.edu.cn.ORCID http://orcid.org/0000-0001-7832-496X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental condition with a 4:1 male bias, yet the biological basis for this sex difference remains poorly understood. Heterozygous mutations in the chromatin remodeler CHD8 confer high risk for ASD, with phenotypes influenced by sex and genetic background. Here, we generated Chd8

Indexed as

Autism spectrum disorderCHD8HippocampusMRISexual dimorphism

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.