ReviewInternational ophthalmology2026
Trends in pathogens causing microbial keratitis in studies conducted in Mexico: a 38-year literature review.
Review in International ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Geographic variation in microbial keratitis: insights from Türkiye.Eye (London, England) · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo review the available literature, including peer-reviewed publications and grey literature, describing the microorganisms and demographic characteristics reported in studies of non-viral microbial keratitis conducted in Mexico.
methodsA comprehensive literature search was conducted on March 10, 2026, using databases including PubMed, Scopus and SciELO. To incorporate grey literature, non-traditional sources such as Google Scholar, ResearchGate, and thesis repositories from ophthalmology training institutions-Universidad Nacional Autónoma de México, Universidad Autónoma de Nuevo León, Tecnológico de Monterrey, and Universidad de Monterrey-were also included.
resultsWe identified 48 studies on infectious keratitis in Mexico (1988-2026), including 14,651 patients. Bacterial keratitis was the most frequent form; gram-positive cocci, especially Staphylococcus epidermidis and Staphylococcus aureus, predominated, whereas Pseudomonas aeruginosa was the leading gram-negative pathogen, particularly among contact lens wearers, with higher frequencies reported in Monterrey and Guadalajara than in Mexico City. Fungal keratitis, reported in 1,446 patients, was mainly caused by Fusarium spp., Aspergillus spp., and Candida albicans, with several dematiaceous fungi also described. Acanthamoeba keratitis was rare (0.3% of infectious keratitis), with only 13 cases reported. Culture positivity and age distribution varied widely across studies. Overall, the reviewed studies show substantial regional heterogeneity with a predominance of gram-positive bacterial pathogens.
conclusionsIn the reviewed studies from Mexico, reported non-viral infectious keratitis cases were most commonly caused by bacteria, particularly gram-positive organisms. Among contact lens wearers, gram-negative bacteria are more frequently isolated. The prevalence of fungal and Acanthamoeba-related keratitis in the available literature appears to align with global trends.
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Registered trials
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