Evidence map›Paper›PMID 42319466›Full record

ReviewDie Anaesthesiologie2026

[Muscle relaxation 2026-50 years of searching for the ideal relaxant].

Thomas Krönauer, Felix Girrbach, Philipp Simon, Axel R Heller

Abstract readReviewHistorical ArticleEnglish Abstract
In one paragraph

Review in Die Anaesthesiologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas KrönauerAnästhesiologie und Operative Intensivmedizin, Medizinische Fakultät, Universität Augsburg, Universitätsklinikum Augsburg, Stenglinstr. 2, 86156, Augsburg, Deutschland. thomas.kroenauer@uk-augsburg.de.
Felix GirrbachAnästhesiologie und Operative Intensivmedizin, Medizinische Fakultät, Universität Augsburg, Universitätsklinikum Augsburg, Stenglinstr. 2, 86156, Augsburg, Deutschland.
Philipp SimonAnästhesiologie und Operative Intensivmedizin, Medizinische Fakultät, Universität Augsburg, Universitätsklinikum Augsburg, Stenglinstr. 2, 86156, Augsburg, Deutschland.
Axel R HellerAnästhesiologie und Operative Intensivmedizin, Medizinische Fakultät, Universität Augsburg, Universitätsklinikum Augsburg, Stenglinstr. 2, 86156, Augsburg, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since its clinical introduction, muscle relaxation has been one of the most specific topics in anesthesiology, due to the clear interaction between physiology and pharmacology and the immediately apparent effects.Beyond the classical indications in anesthesia for securing the airway, many modern surgical procedures and interventions would not be possible without the development of muscle relaxation; however, warnings about the associated risks and complications have also been issued for decades.Following the expiration of the patent protection of sugammadex in summer 2023, its specific effects and favorable side-effect profile have made a significant contribution to the simplification of muscle relaxation management; however, nearly 2 years later it is important to acknowledge that this advantageous development does not guarantee complete safety and that clinical risks continue to exist in connection with muscle relaxation.Therefore, in this field profound physiological and pharmacological knowledge stay just as important as a consistent and thorough work ethic in accordance with the current guidelines of the anesthesia professional associations.

Indexed as

Muscle RelaxationHumansNeuromuscular Nondepolarizing AgentsSugammadexNeuromuscular Nondepolarizing AgentsSugammadexNeostigminNeuromuscular monitoringRocuroniumSugammadexSuxamethonium

Identifiers

PMID42319466
PMCPMC13323612

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.