Evidence map›Paper›PMID 42319248›Full record

ArticleJournal of the International AIDS Society2026

From Policy to Practice: Brazil's Pathway to Eliminating Vertical Transmission of HIV as a Public Health Milestone.

Pâmela Cristina Gaspar, Angélica Espinosa Miranda, Leonor Henriette de Lannoy, Ana Roberta Pati Pascon, Carmen Silvia Bruniera Domingues, Ítalo Vinicius Albuquerque Diniz, Amanda Krummenauer, Ana Paula Betaressi da Silva, Alisson Bigolin, Ariane Tiago Bernardo de Matos and 7 more

Abstract read
In one paragraph

Article in Journal of the International AIDS Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Progress and Challenges in Elimination of Vertical HIV Transmission.Journal of the International AIDS Society · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Pâmela Cristina GasparDepartment of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.
Angélica Espinosa MirandaPostgraduate Program in Infectious Diseases, Health Sciences Center, Federal University of Espírito Santo, Vitória, Brazil.
Leonor Henriette de LannoyDepartment of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.ORCID https://orcid.org/0000-0002-9520-8538
Ana Roberta Pati PasconDepartment of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.
Carmen Silvia Bruniera DominguesDepartment of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.
Ítalo Vinicius Albuquerque DinizDepartment of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.
Amanda KrummenauerDepartment of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.
Ana Paula Betaressi da SilvaDepartment of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.
Alisson BigolinDepartment of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.
Ariane Tiago Bernardo de MatosDepartment of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.
Márcia Rejane ColomboDepartment of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.
Claudia Gonçalves SiqueiraDepartment of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.
Angela Gasperin MartinazzoDepartment of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.
Adele Schwartz BenzakenHeitor Vieira Dourado Tropical Medicine Foundation, State University of Amazonas (UEA), Manaus, Brazil.
Draurio BarreiraDepartment of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections, Secretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.
Mariângela Batista Galvão SimãoSecretariat for Health and Environmental Surveillance, Ministry of Health of Brazil, Brasília, Brazil.
Brazilian Elimination Vertical Transmission Group (Brazilian EVT Group)

Funding

Department of HIV, AIDS, Tuberculosis, Viral Hepatitis, and Sexually Transmitted Infections-Dathi, Secretariat for Health and Environmental Surveillance-SVSA, Ministry of Health of Brazil
6 · The paper itself

Abstract

introductionThe elimination of vertical transmission of HIV is a global health priority endorsed by the Pan American Health Organization (PAHO) and the World Health Organization (WHO), aligned with the Sustainable Development Goals (SDGs). Brazil has made substantial progress towards this goal through sustained investment in universal health policies and a rights-based approach to healthcare. DISCUSSION: Brazil's national HIV response is anchored in the Unified Health System (Sistema Único de Saúde-SUS), a universal, decentralized and participatory health system that ensures access to prevention, diagnosis, treatment and monitoring. Tripartite governance-across federal, state and municipal levels-combined with strong community engagement, has enabled coordinated policy implementation at scale. This framework has supported high coverage of antenatal care (>98%), HIV testing (>95%) and antiretroviral therapy among pregnant women living with HIV (>95%) in recent years. Vertical transmission rates of HIV declined from 3.73% in 2015 to 1.78% in 2023, remaining below the elimination threshold. The annual rate of new paediatric HIV acquisitions also declined to low levels, being 5.99 per 100,000 live births in 2023, far below the PAHO/WHO targets. A certification for states and municipalities strategy further accelerated progress toward the elimination by strengthening accountability, improving data quality and engaging local health systems.

conclusionsBrazil's experience demonstrates that HIV vertical transmission elimination is feasible in large and unequal settings when supported by strong governance, integrated health systems and sustained political commitment. The certification of vertical transmission elimination of HIV by PAHO/WHO in 2025 represents a major milestone and offers valuable lessons for global health. Brazil remains committed to sustaining stainability of this certification and to advancing efforts for the elimination of other vertically transmitted infections, including syphilis, hepatitis B, Human T-cell lymphotropic virus (HTLV) and Chagas disease.

Indexed as

Disease EradicationHealth PolicyHIV InfectionsInfectious Disease Transmission, VerticalPublic HealthBrazilFemaleHumansPregnancyPregnancy Complications, Infectiouscertificationcommunity engagementeliminationhealth plan implementationHIVinfectious disease transmissionuniversal healthcarevertical

Identifiers

PMID42319248
PMCPMC13281404

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.