Evidence map›Paper›PMID 42318876›Full record

Trial reportMaternal & child nutrition2026

Effect of Home-Based Multiple Micronutrient Powder Fortification on Haemoglobin Levels in Infants in Nampula, Mozambique: A Pragmatic Clinical Trial.

Ana Raquel Ernesto Manuel Gotine, Marly Augusto Cardoso

Abstract readRandomized Controlled TrialPragmatic Clinical Trial
In one paragraph

Trial report in Maternal & child nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ana Raquel Ernesto Manuel GotinePostgraduate Program in Public Health, University of São Paulo (USP), São Paulo, São Paulo, Brazil.ORCID 0000-0002-3539-4236
Marly Augusto CardosoDepartment of Nutrition, School of Public Health, São Paulo, São Paulo, Brazil.ORCID 0000-0003-0973-3908

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To conduct a pragmatic clinical trial with multiple micronutrient powders (MNPs) for anaemia prevention during the first year of life in primary care in Nampula, Mozambique. A total of 275 infants, aged 6-8 months, were randomly assigned to intervention (IG, n = 145) and control (CG, n = 130) groups. The IG received 90 sachets of MNP for daily use up to 180 days; the CG received standard care. Haemoglobin (Hb) was measured at baseline and after 6 months. Analysis used linear regression adjusted for child and maternal variables (p < 0.05). At baseline, mean Hb (95% CI) was 102.2 g/L (100.4-104.0) in the IG and 103.8 g/L (102.0-105.7) in the CG, with corresponding anaemia rates (Hb < 105 g/L) of 55.2% (47.1; 63.0%) and 47.7% (39.3; 56.2%). After intervention, IG had 106.2 g/L (104.2-108.1) vs CG 99.5 g/L (97.3-101.8), with anaemia rates of 36% (27.8; 45.1) and 67.3% (57.9; 75.4), respectively. Adjusted mean intra-group difference of haemoglobin (g/L) from baseline to follow-up was +2.8 in IG and -4.3 in CG. MNPs improved haemoglobin levels, supporting their potential for anaemia control in vulnerable populations.

trial registrationhttps://ensaiosclinicos.gov.br/rg/RBR-4r37q7z. Registered 11/11/2024.

Indexed as

AnemiaAnemia, Iron-DeficiencyFood, FortifiedHemoglobinsMicronutrientsDietary SupplementsFemaleHumansInfantInfant Nutritional Physiological PhenomenaMaleMozambiquePowdersHemoglobinsMicronutrientsPowdersanaemiacomplementary feedinghome fortificationiron deficiencymicronutrients

Identifiers

PMID42318876
PMCPMC13280800

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.