Evidence map›Paper›PMID 42318831›Full record

ArticleJournal of surgical oncology2026

New Paradigms of Cancer Require New Language: A Qualitative Study Exploring Language for Non-Curative Non-Palliative Cancer Surgery.

Bonnie O Wong, Orly N Farber, Amanda J Reich, Zara R Cooper, Jennifer W Mack, Thomas E Clancy, Chandrajit P Raut, Elizabeth J Lilley

Abstract read
In one paragraph

Article in Journal of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bonnie O WongDepartment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-8363-8285
Orly N FarberDepartment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Amanda J ReichCenter for Surgery and Public Health at Brigham and Women's Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-5922-4154
Zara R CooperDepartment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Jennifer W MackDivision of Population Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Thomas E ClancyDepartment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Chandrajit P RautDepartment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Elizabeth J LilleyDepartment of Surgery, Brigham and Women's Hospital, Boston, Massachusetts, USA.

Funding

RESEARCH TRAINING IN ALIMENTARY TRACT SURGERYT32DK007754 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI HODIN, RICHARD A. · 1997 to 2025
$6.5M
Training in Oncology Population Sciences (TOPS)T32CA092203 · NCI · DANA-FARBER CANCER INST · PI Nancy L Keating, JENNIFER W MACK · 2018 to 2026
$3.7M
National Institute of Health T32DK007754-25NCI NIH HHS T32 CA092203NCI NIH HHS T32CA092203-22NIDDK NIH HHS T32 DK007754
6 · The paper itself

Abstract

BACKGROUND AND

methodsCancer interventions are traditionally described as either "curative" or "palliative," but evolving cancer biology and new treatments have transformed some cancers into chronic diseases where surgery plays a non-curative, disease-targeted role. We conducted semi-structured interviews with cancer surgeons via purposive snowball sampling, exploring two hypothetical scenarios and discussing "disease-control" surgery as a category of neither palliative nor curative surgical intent. Interviews were thematically analyzed.

resultsEighteen surgeons from 16 US institutions described how evolving cancer treatment paradigms challenge existing language for surgical intent. "Disease-control" surgery captured new adjuvant surgical roles including debulking to improve systemic therapy efficacy, resection of treatment-resistant disease, and "resetting the clock" for indolent tumors. Surgical goals are increasingly defined by individual patients' broader multidisciplinary treatment trajectory.

conclusionsTraditional "curative" versus "palliative" categories inadequately describe contemporary cancer surgery. New frameworks aligned with current understandings of cancer biology and new treatment modalities may facilitate clearer communication about surgical goals and enable developing appropriate research outcome measures. DISCUSSION: These findings highlight a need for standardized surgical intent terminology. Broader validation through multidisciplinary stakeholder engagement is needed to refine and implement this proposed framework.

Indexed as

NeoplasmsSurgeonsTerminology as TopicFemaleHumansMalePalliative CareQualitative Researchgoals of careneoplasms surgerypalliative carequalitative researchterminology as topic

Identifiers

PMID42318831
PMCPMC13532940

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.