ArticleBioMed research international2026
Rapid Measurement of Erythrocyte Sedimentation Rate Using a Tube Positioned at a 45° Angle Compared With the Westergren Reference Method.
Article in BioMed research international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Rapid Measurement of Erythrocyte Sedimentation Rate Using a Tube Positioned at a 45° Angle Compared With the Westergren Reference Method.BioMed research international · 2026Article
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12 authors.
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Abstract
backgroundThe erythrocyte sedimentation rate (ESR) is a routine hematological test that can detect and track an increase in the body's inflammatory activity caused by infections, tumors, or autoimmune diseases. Although the test has lower specificity than C-reactive protein in assessing inflammation, it is widely used in resource-limited countries such as Ghana due to its low cost and ease of performance. The conventional Westergren method of ESR estimation takes 1 h, and this could hinder the availability of results in routine clinical workflows. It is in view of this that the present study sought to reduce the turnaround time without compromising on test accuracy by using a method that involved positioning the tube at an angle of 45°.
methodsThis experimental analytical method comparison study recruited 100 participants (50 pregnant and 50 healthy blood donors) aged between 15 and 40 years. Five milliliters of venous blood was taken from each participant and added to trisodium citrate anticoagulant in a fixed blood-to-anticoagulant ratio of 4:1. For each study participant, two Westergren-Katz tubes were filled with the diluted blood to the 200 mm mark, and one was held vertically at 90° while the other was set at an angle of 45° at room temperature. The ESR value was recorded after 1 h for the vertically (90°) set tube, while the ESR value was read every minute for 10 min for the tube placed at an angle of 45°.
resultsESR results obtained from the 6
conclusionThis study proved that the turnaround time for the ESR test could be reduced to 8 min if the tube is positioned at an angle of 45°.
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