Evidence map›Paper›PMID 42318765›Full record

ArticleBritish journal of haematology2026

Glomeruloid haemangioma in Erdheim-Chester disease: An atypical skin manifestation associated with elevated vascular endothelial growth factor-A levels.

Jerome Razanamahery, Matthias Papo, Francesco Pegoraro, Felix Blaison, Paul Legendre, Valentin Carado, Martin Caretti, Aubriot Lorton Marie Helene, Jean-Francois Emile, Augusto Vaglio and 1 more

Abstract readLetter
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In one paragraph

Article in British journal of haematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jerome RazanamaheryDepartment of Internal Medicine and Clinical Immunology, Dijon University Hospital, Dijon, France.
Matthias PapoDepartment of Internal Medicine 2, French Reference Center for Histiocytosis, Pitie Salpetriere Hospital, Paris, France.ORCID https://orcid.org/0000-0003-3389-9473
Francesco PegoraroDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0002-4954-5744
Felix BlaisonDepartment of Internal Medicine, Bordeaux University Hospital, Bordeaux, France.
Paul LegendreClinical Immunology Department, Le Mans Hospital, Le Mans, France.
Valentin CaradoDepartment of Dermatology, Dijon University Hospital, Dijon, France.
Martin CarettiDepartment of Dermatology, Dijon University Hospital, Dijon, France.
Aubriot Lorton Marie HeleneDepartment of Pathology, Dijon University Hospital, Dijon, France.
Jean-Francois EmileDepartment of Pathology, Ambroise Pare Hospital, Boulogne-Billancourt, France.ORCID https://orcid.org/0000-0002-6073-4466
Augusto VaglioDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Julien HarocheDepartment of Internal Medicine 2, French Reference Center for Histiocytosis, Pitie Salpetriere Hospital, Paris, France.ORCID https://orcid.org/0009-0003-9794-1316

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glomeruloid haemangiomas and extensive angiomas occurred in a small subset of Erdheim-Chester disease patients, all showing markedly elevated vascular endothelial growth factor-A (VEGF-A) levels despite the absence of POEMS (polyneuropathy, organomegaly, M-spike, and skin disease) syndrome. Molecular analyses demonstrated mitogen-activated protein kinase (MAPK)-activated histiocytes without endothelial mutations, supporting a paracrine VEGF-A-driven angiogenesis mechanism underlying these atypical cutaneous lesions.

Indexed as

Erdheim-Chester DiseaseHemangiomaSkin NeoplasmsVascular Endothelial Growth Factor AFemaleHistiocytesHumansMaleVascular Endothelial Growth Factor AVEGFA protein, humanangiomaECDhistiocytosisVEGF‐A

Identifiers

PMID42318765
PMCPMC13462258

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.