Evidence map›Paper›PMID 42318567›Full record

Trial reportFrontiers in dental medicine2026

Antibacterial effectiveness of novel polyherbal gel, chlorhexidine gluconate, and calcium hydroxide as intracanal medicaments in infected root canals using real-time PCR: a randomized controlled trial.

Anil V Ankola, Vinuta Hampiholi, Ram Surath Kumar, Manohar S Kugaji, Roopali M Sankeshwari, Varkey Nadakkavukaran Santhosh, Atrey J Pai Khot, Kavitha Ragu, Mohammed Mustafa, Ahmed A Almokhatieb

Abstract readClinical Trial
In one paragraph

Trial report in Frontiers in dental medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anil V AnkolaDepartment of Public Health Dentistry, KLE Vishwanath Katti Institute of Dental Sciences, KLE Academy of Higher Education and Research, Belagavi, India.
Vinuta HampiholiDepartment of Periodontics, KLE Vishwanath Katti Institute of Dental Sciences, KLE Academy of Higher Education and Research, Belagavi, India.
Ram Surath KumarDepartment of Public Health Dentistry, KLE Vishwanath Katti Institute of Dental Sciences, KLE Academy of Higher Education and Research, Belagavi, India.
Manohar S KugajiCentre for Advanced Medical Research (CAMR), BLDE (Deemed to be University), Bangaramma Sajjan Campus, Vijaypura, India.
Roopali M SankeshwariDepartment of Public Health Dentistry, KLE Vishwanath Katti Institute of Dental Sciences, KLE Academy of Higher Education and Research, Belagavi, India.
Varkey Nadakkavukaran SanthoshDepartment of Public Health Dentistry, KLE Vishwanath Katti Institute of Dental Sciences, KLE Academy of Higher Education and Research, Belagavi, India.
Atrey J Pai KhotDepartment of Public Health Dentistry, KLE Vishwanath Katti Institute of Dental Sciences, KLE Academy of Higher Education and Research, Belagavi, India.
Kavitha RaguDepartment of Public Health Dentistry, KLE Vishwanath Katti Institute of Dental Sciences, KLE Academy of Higher Education and Research, Belagavi, India.
Mohammed MustafaDepartment of Conservative Dental Sciences, College of Dentistry, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
Ahmed A AlmokhatiebDepartment of Conservative Dental Sciences, College of Dentistry, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aimed to evaluate the antibacterial effectiveness of three intracanal medicaments: Methods: A triple-arm, randomized controlled trial was conducted on 45 permanent mandibular and maxillary incisor and canine teeth diagnosed with asymptomatic apical periodontitis. Participants were randomly divided into three equal groups ( Results: All the groups showed a significant reduction in Conclusions: All three intracanal medicaments tested were effective in significantly reducing Trial registration: [https://ctri.nic.in/Clinicaltrials/pmaindet2.php?EncHid=NjU0MzY=] Clinical Trials Registry-India with registration number: [CTRI/2022/07/043862].

Indexed as

anti-Bacterial agentscalcium hydroxidechlorhexidineenterococcus faecalisherbalintracanal medication

Identifiers

PMID42318567
PMCPMC13272454

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.