Evidence map›Paper›PMID 42318421›Full record

SynthesisFrontiers in medicine2026

Effect of transversus abdominis plane block on postoperative pain after nephrectomy: a systematic review.

Wei Huang, JinPing Wang, Yu Du, Ji Wang

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wei Huang *Department of Anaesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
JinPing Wang *Department of Anaesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Yu DuDepartment of Anaesthesiology, The Affiliated Nanchong Central Hospital of North Sichuan Medical College, Beijing Anzhen Nanchong Hospital of Capital Medical University and Nanchong Central Hospital, Nanchong, Sichuan, China.
Ji WangDepartment of Anaesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To systematically evaluate the effect of transversus abdominis plane block (TAPB) on postoperative analgesia after nephrectomy. Methods: A computerised search was conducted to identify randomised controlled trials (RCTs) evaluating TAPB for postoperative analgesia after nephrectomy from database inception to 31 January 2026 in the Cochrane Library, PubMed, Embase, Web of Science, China Biomedical Literature Service, Wanfang Data, and the China National Knowledge Infrastructure. Two researchers independently screened the literature, extracted data, and assessed the risk of bias of the included studies. Meta-analysis was performed using Review Manager 5.4. The quality of evidence was graded using the GRADEpro system, and publication bias for endpoint indicator was assessed using Stata 17.0. Results: Ten RCTs involving a total of 639 patients were included. The meta-analysis showed that, compared with the control group, the TAPB group demonstrated a significant reduction in intravenous morphine equivalents at 24-hour postoperative [MD = -16.67, 95% CI (-25.57, -7.77), Conclusion: Except for the absence of significant differences in resting pain scores at 2 and 4 hours postoperative, TAPB might reduce postoperative pain after nephrectomy, decreased postoperative opioid consumption, lowered postoperative pain scores, and reduced gastrointestinal adverse reactions.

Indexed as

nephrectomypostoperative analgesiarandomised controlled trialsystematic reviewtransversus abdominis plane block

Identifiers

PMID42318421
PMCPMC13272322

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.