ArticleFrontiers in medicine2026
Delta MEWS combined with SpO
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Objective: To develop and validate a practical model to identify MEWS-based high-alert physiologic status at the time of unplanned transfer to the emergency resuscitation room (UTER) among emergency patients under observation. Methods: This multicenter retrospective study used complete-case data from three hospitals in China. The training cohort comprised 599 UTER patients from the First Hospital of Jilin University (January 1 - December 31, 2023). Temporal internal validation included 145 UTER patients from the same hospital (January 1 - March 31, 2024). Geographic external validation included 231 UTER patients from Hainan Provincial People's Hospital and the Second Hospital of Shanxi Medical University (December 1, 2022 - March 1, 2023). M1 was the MEWS within 1 h after entry to the emergency observation room; M2 was the MEWS at UTER; Delta MEWS = M2 - M1. The modeled endpoint was MEWS-based high-alert status at UTER, defined as M2 ≥ 6. Logistic regression, nomogram construction, ROC analysis, calibration analysis, and decision-curve analysis were used. The positive class for precision-recall analysis was prespecified as MEWS-based high-alert status at UTER (M2 ≥ 6). Results: In the training cohort, the optimal training-set cutoff for Delta MEWS was 3.5, corresponding to a sensitivity of 0.837 and a specificity of 0.924. In multivariable analysis, SpO Conclusion: Delta MEWS combined with SpO
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