SynthesisFrontiers in medicine2026
Transcutaneous electrical acupoint stimulation for preventing postoperative nausea and vomiting in patients undergoing breast surgery: a systematic review and meta-analysis of randomized controlled trials.
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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4 authors.
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Abstract
Background: Postoperative nausea and vomiting (PONV) remains a frequent challenge for patients undergoing breast cancer surgery. Transcutaneous electrical acupoint stimulation (TEAS) is increasingly utilized as a needle-free, neuromodulatory adjunct in perioperative care. Although a prior meta-analysis evaluated TEAS for PONV across general surgical populations, breast surgery-specific evidence remains lacking. This meta-analysis evaluates the efficacy of TEAS for preventing PONV and enhancing early recovery in this specific surgical population. Methods: We systematically searched PubMed, Embase, Cochrane Library, Web of Science, and three Chinese databases (CNKI, VIP, Wanfang) for randomized controlled trials (RCTs) comparing perioperative TEAS with sham stimulation or routine care, up to March 10, 2026. The primary outcome was overall PONV incidence. Secondary outcomes included postoperative nausea, vomiting, pain scores, and early recovery quality (QoR). Data were synthesized using RevMan 5.4, and the certainty of evidence was assessed with GRADE. Results: Fifteen RCTs comprising 1,752 patients were included. TEAS significantly reduced overall PONV risk [RR = 0.61, 95% CI (0.49, 0.77), Conclusion: TEAS might be an effective and non-pharmacological adjunct for reducing PONV and supporting early recovery in breast cancer surgery. These findings support its integration into perioperative care, although further large-scale, sham-controlled RCTs are warranted to establish standardized protocols. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/view/CRD420261333755.
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