ArticleFrontiers in medicine2026
Impact of hospice care plus estazolam on sleep and psychological distress in advanced gastrointestinal cancer: a real-world observational study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To retrospectively evaluate the effects of hospice care combined with estazolam on sleep quality and psychological status in patients with advanced gastrointestinal cancer. Methods: In accordance with our predefined inclusion and exclusion criteria, this study retrospectively enrolled 110 inpatients with advanced gastrointestinal cancer and sleep disturbances who received treatment at our hospital between January 2019 and January 2025. Participants were assigned to two groups based on the treatment documented in their medical records: the hospice care plus estazolam group ( Results: After 1 month of treatment, the hospice-care plus estazolam group showed greater improvements than the routine nursing plus estazolam group: PSQI (sleep quality) mean difference between groups was significant ( Conclusion: This retrospective analysis suggests that hospice care combined with estazolam is associated with significantly better sleep quality, psychological wellbeing, and overall quality of life in patients with advanced gastrointestinal cancer compared to routine nursing with estazolam alone. However, due to the retrospective design and short 1-month follow-up, causality cannot be inferred, and the study has limitations including a relatively small sample size, single-center design, and short follow-up duration. Future prospective studies with larger samples and longer follow-up are needed to confirm these findings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.