ArticleJournal of inflammation research2026
The Clinical Significance and Prognostic Value of Inflammatory Hematological Indices in Young Patients with Coronary Artery Disease.
Article in Journal of inflammation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Predictive value of systemic inflammatory response index for coronary artery disease and angiographic severity: a single-center retrospective study.Frontiers in cardiovascular medicine · 2026Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study primarily investigates the relationship between inflammatory hematological indices [neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), systemic immune inflammation index (SII), system inflammation response index (SIRI), and pan-immune inflammation value (PIV)] and acute coronary syndrome (ACS) in young patients, with secondary objectives to explore their association with coronary artery disease (CAD) severity and long-term prognosis. Methods: This observational study enrolled 986 CAD patients (aged 18-35 years) undergoing coronary angiography at Beijing Anzhen Hospital between January 2013 and December 2021. Participants were divided into ACS and non-ACS groups and further stratified by Gensini score into mild, moderate, and severe lesion groups. Patients were followed for a median of 8 years for major adverse cardiovascular events (MACE). Statistical analyses included Spearman correlation, ROC curves, and logistic regression to evaluate the relationships between inflammatory indices and ACS, coronary severity, and long-term outcomes. Results: The prevalence of ACS progressively increased with higher quartiles of NLR, PLR, MLR, SII, SIRI, and PIV ( Conclusion: In young patients with CAD, SIRI and PIV are valuable for ACS prediction, and several indices correlate with lesion severity. However, their limited long-term prognostic utility suggests distinct pathological mechanisms may govern disease progression in this unique population.
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