Evidence map›Paper›PMID 42318273›Full record

ArticleJournal of sports science & medicine2026

Blood Flow Restriction Training Reduces Hemodynamic Load and Improves Cardiovascular Biomarkers in Runners with Exercise-Induced Hypertension.

Young-Joo Kim, Choung-Hwa Park, Han-Soo Park, Yu-Eun Lim

Abstract read
In one paragraph

Article in Journal of sports science & medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Young-Joo KimSchool of Sports Science, SungshinWomen's University, Seoul, Republic of Korea.
Choung-Hwa ParkGraduate School of Alternative Medicine, Kyonggi University, Seoul, Republic of Korea.
Han-Soo ParkSports Medicine Laboratory, Korea National Sport University, Seoul, Republic of Korea.
Yu-Eun LimSports Medicine Laboratory, Korea National Sport University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exercise-induced hypertension (EIH) is associated with elevated risks of arrhythmia, coronary artery disease, arterial stiffness, and sudden cardiac death. Blood flow restriction (BFR) training has been proposed as a non-pharmacological intervention. This study aimed to evaluate whether changes in cardiovascular biomarkers accompanied hemodynamic improvements following BFR training in middle-aged runners with EIH. This secondary analysis included 28 male runners with EIH (mean age: 57.4 ± 6.5 years) from a prior cohort applying the same BFR training protocol. Participants exhibited a maximal systolic blood pressure ≥210 mmHg during graded exercise testing (GXT) and were assigned to a BFR training group (BFRTg, n = 16) or a control group (non-BFRTg, n = 12). BFR training was performed twice weekly for 20 minutes over 8 weeks. Cardiorespiratory fitness and hemodynamic response during GXT were also assessed. Cardiovascular biomarkers (endothelin-1 [ET-1], high-sensitivity C-reactive protein [hs-CRP], NT-proBNP, and nitric oxide [NO]) were measured pre- and post-intervention. In the BFRTg, ET-1, hs-CRP, and NT-proBNP levels decreased after BFR training, while maximal systolic blood pressure decreased and VO

Indexed as

Blood Flow Restriction TherapyHemodynamicsHypertensionRunningBiomarkersBlood PressureCardiorespiratory FitnessC-Reactive ProteinEndothelin-1Exercise TestHumansMaleMiddle AgedNatriuretic Peptide, BrainNitric OxidePeptide FragmentsBiomarkersC-Reactive ProteinEndothelin-1Natriuretic Peptide, BrainNitric OxidePeptide Fragmentspro-brain natriuretic peptide (1-76)Blood flow restrictioncardiovascular markersendothelial functionexercise-induced hypertensioninflammationnitric oxide

Identifiers

PMID42318273
PMCPMC13274443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.