Evidence map›Paper›PMID 42318030›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2026

Structure, personnel, and initiatives of antimicrobial stewardship programs in pediatric hospitals in the United States based on on-call participation: a cross-sectional survey.

Gustavo Rey Alvira-Arill, Samantha Brace, Taylor Morrisette, Stephen Thacker, Aaron Hamby, Rachel Burgoon, Zachary Gruss, Alexandra Mills, Richard Lueking, Krutika Mediwala Hornback

Abstract read
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gustavo Rey Alvira-ArillDepartment of Clinical Pharmacy and Outcomes Sciences, Medical University of South Carolina, Charleston, USA.ORCID https://orcid.org/0000-0003-3138-8848
Samantha BraceDepartment of Pharmacy, Cape Fear Valley Health, Fayetteville, USA.ORCID https://orcid.org/0009-0002-8807-1964
Taylor MorrisetteDepartment of Clinical Pharmacy and Outcomes Sciences, Medical University of South Carolina, Charleston, USA.ORCID https://orcid.org/0000-0002-1094-043X
Stephen ThackerDepartment of Pediatrics, Division of Infectious Diseases, Medical University of South Carolina, Charleston, USA.ORCID https://orcid.org/0000-0002-3410-4524
Aaron HambyDepartment of Pharmacy Services, Medical University of South Carolina, Charleston, USA.ORCID https://orcid.org/0000-0003-2600-7393
Rachel BurgoonDepartment of Pharmacy Services, Medical University of South Carolina, Charleston, USA.ORCID https://orcid.org/0000-0003-3291-7174
Zachary GrussDepartment of Pharmacy Services, Medical University of South Carolina, Charleston, USA.ORCID https://orcid.org/0000-0002-6238-0331
Alexandra MillsDepartment of Internal Medicine, Division of Infectious Diseases, Medical University of South Carolina, Charleston, USA.ORCID https://orcid.org/0000-0002-4473-8096
Richard LuekingDepartment of Internal Medicine, Division of Infectious Diseases, Medical University of South Carolina, Charleston, USA.ORCID https://orcid.org/0000-0003-2029-0415
Krutika Mediwala HornbackDepartment of Pharmacy Services, Medical University of South Carolina, Charleston, USA.ORCID https://orcid.org/0000-0002-3982-2103

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antimicrobial stewardship programs (ASPs) promote optimal antimicrobial use in pediatrics; however, data describing structure, personnel effort allocation, and activity distribution across regular and after-hours workflows remain limited. Methods: We conducted a cross-sectional survey of pediatric ASPs across the U.S. from September to October 2024 using ASP/ID-related listservs. Respondents reported institutional structure, personnel effort allocation, initiatives, and participation in an after-hours ASP on-call model, with additional details from programs reporting on-call participation. Results: Twenty-two pediatric ASP responses were included, most from academic medical centers (81.8%) and programs covering 101-250 beds (41%). Median physician full-time equivalents (FTEs) increased with institutional size, ranging from 0.1 for institutions with < 100 beds to 0.8 for those with >500 beds. Pharmacist FTEs were a median of 1 for institutions with ≤ 500 beds and increased to 2.25 for programs >500 beds. Most programs reported to Quality and Safety (45%) or discipline-specific departments (41%), with funding primarily attributed to Pharmacy (73%). During regular working hours, nearly all programs performed prospective audit and feedback (100%), responded to ASP-related inquiries (95.5%), and facilitated antimicrobial de-escalation (90.9%). Six programs (27.4%) reported participation in an ASP on-call model, most commonly providing remote coverage during evenings, weekends, and holidays. After-hours activities were largely limited to time-sensitive interventions, including preauthorization and responding to inquiries. Conclusions: Pediatric ASPs demonstrate variability in structure, personnel effort allocation, and stewardship activities. ASP on-call coverage remains uncommon and is typically focused on time-sensitive interventions, reflecting targeted deployment of stewardship resources outside regular working hours.

Identifiers

PMID42318030
PMCPMC13273151

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.